(Z)-4-Hydroxytamoxifen, estrogen receptor modulator (ab141943)
Key features and details
- Potent and selective estrogen receptor modulator
- CAS Number: 68047-06-3
- Purity: > 98%
- Soluble in ethanol to 50 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
(Z)-4-Hydroxytamoxifen, estrogen receptor modulator -
製品の詳細
Potent and selective estrogen receptor modulator -
別名
- 4-OHT
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精製度
> 98% -
CAS 番号
68047-06-3 -
構造式
製品の特性
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体系名
4-[(Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol -
分子量
387.52 -
分子式
C26H29NO2 -
PubChem 登録番号
449459 -
保存方法
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in ethanol to 50 mM and in DMSO to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3 -
由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (10)
ab141943 は 10 報の論文で使用されています。
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- Yoshida K et al. Microscopic Detection of DNA Synthesis in Early Mitosis at Repetitive lacO Sequences in Human Cells. Bio Protoc 12:N/A (2022). PubMed: 36213106
- Sula A et al. A tamoxifen receptor within a voltage-gated sodium channel. Mol Cell 81:1160-1169.e5 (2021). PubMed: 33503406
- Zink J et al. EVL regulates VEGF receptor-2 internalization and signaling in developmental angiogenesis. EMBO Rep 22:e48961 (2021). PubMed: 33512764
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- Kyprianou C et al. Basement membrane remodelling regulates mouse embryogenesis. Nature 582:253-258 (2020). PubMed: 32523119
- Crawford M et al. Essential Role for Integrin-Linked Kinase in Melanoblast Colonization of the Skin. J Invest Dermatol N/A:N/A (2019). PubMed: 31330146
- Bartels M et al. Iron-mediated aggregation and toxicity in a novel neuronal cell culture model with inducible alpha-synuclein expression. Sci Rep 9:9100 (2019). PubMed: 31235814
- Itkonen HM et al. High OGT activity is essential for MYC-driven proliferation of prostate cancer cells. Theranostics 9:2183-2197 (2019). PubMed: 31149037
- Hatzistergos KE et al. cKit+ cardiac progenitors of neural crest origin. Proc Natl Acad Sci U S A 112:13051-6 (2015). PubMed: 26438843