Anti-WRNIP1/WHIP 抗体 (ab18729)
Key features and details
- Goat polyclonal to WRNIP1/WHIP
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-WRNIP1/WHIP antibody
WRNIP1/WHIP 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to WRNIP1/WHIP -
由来種
Goat -
アプリケーション
適用あり: IHC-P, WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Cow, Dog -
免疫原
Synthetic peptide corresponding to Human WRNIP1/WHIP aa 652-665 (C terminal).
Sequence:EELRGVDFFKQRRC
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituent: 0.5% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab18729の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
Use a concentration of 4 - 6 µg/ml. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
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WB |
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 72 kDa.
1 hour primary incubation is recommended for this product. |
特記事項 |
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IHC-P
Use a concentration of 4 - 6 µg/ml. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol. |
WB
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 72 kDa. 1 hour primary incubation is recommended for this product. |
ターゲット情報
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機能
Functions as a modulator for initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. Has an intrinsic ATPase activity that functions as a sensor of DNA damage or of arrested replication forks and regulates the extent of DNA synthesis. -
組織特異性
Ubiquitously expressed. -
配列類似性
Belongs to the AAA ATPase family.
Contains 1 UBZ-type zinc finger. -
翻訳後修飾
Sumoylated by SUMO1 and SUMO2/3. -
細胞内局在
Nucleus. Colocalizes with WRN in granular structures in the nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 56897 Human
- Entrez Gene: 78903 Mouse
- Entrez Gene: 282835 Rat
- Omim: 608196 Human
- SwissProt: Q96S55 Human
- SwissProt: Q91XU0 Mouse
- SwissProt: Q8CG07 Rat
- Unigene: 236828 Human
see all -
別名
- ATPase WRNIP 1 antibody
- ATPase WRNIP1 antibody
- bA420G6.2 antibody
see all
画像
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ab18729 (4µg/ml) staining of paraffin embedded Human Kidney following steamed antigen retrieval with Tris/EDTA buffer pH 9 and HRP-staining shows nuclear staining, stronger in DCT compared to PCT.
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Anti-WRNIP1/WHIP antibody (ab18729) at 1 µg/ml + Jurkat Cell Lysate in RIPA Buffer at 35 µg
Developed using the ECL technique.
Predicted band size: 72 kDa
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (0)
ab18729 は論文での使用が確認できていません。