Rabbit polyclonal to VTA1
Mouse, Rat, Cow
Recombinant fragment, corresponding to a sequence within amino acids 1-246 of Human VTA1
H1299, HeLaS3, Molt4 whole cell lysates; SW480 xenograft tissue.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol, 1.21% Tris, 0.75% Glycine
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 34 kDa.
1/100 - 1/500.
Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR (By similarity). Involved in HIV-1 budding.
Belongs to the VTA1 family.
Cytoplasm. Endosome membrane.
Information by UniProt
Chromosome 6 open reading frame 55 antibody
Dopamine responsive protein DRG 1 antibody
Western blot - Anti-VTA1 antibody (ab96738)
All lanes : Anti-VTA1 antibody (ab96738) at 1/1000 dilution Lane 1 : H1299 whole cell lysate Lane 2 : HeLaS3 whole cell lysate Lane 3 : Molt4 whole cell lysate Lysates/proteins at 30 µg per lane. Predicted band size: 34 kDa 12% SDS-PAGE.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-VTA1 antibody (ab96738)
ab96738 at 1/500 dilution staining VTA1 in SW480 xenograft by Immunohistochemistry, Paraffin-embedded tissue.
has not yet been referenced specifically in any publications.
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