Anti-VMAT2 抗体 (ab70808)
Key features and details
- Rabbit polyclonal to VMAT2
- Suitable for: IHC-P, ICC/IF, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
製品の概要
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製品名
Anti-VMAT2 antibody
VMAT2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to VMAT2 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-P, ICC/IF, WBmore details -
種交差性
交差種: Mouse, Rat, Human -
免疫原
Synthetic peptide corresponding to internal residues of human, mouse and rat VMAT2.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab70808の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
Use at an assay dependent concentration.
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ICC/IF |
Use at an assay dependent concentration. PubMed: 26755131
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WB |
Use at an assay dependent concentration.
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特記事項 |
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IHC-P
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. PubMed: 26755131 |
WB
Use at an assay dependent concentration. |
ターゲット情報
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機能
Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis. -
配列類似性
Belongs to the major facilitator superfamily. Vesicular transporter family. -
細胞内局在
Cytoplasmic vesicle membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 6571 Human
- Entrez Gene: 214084 Mouse
- Entrez Gene: 25549 Rat
- Omim: 193001 Human
- SwissProt: Q05940 Human
- SwissProt: Q8BRU6 Mouse
- SwissProt: Q01827 Rat
- Unigene: 596992 Human
see all -
別名
- 1110037L13Rik antibody
- 9330105E13 antibody
- MGC120477 antibody
see all
データシートおよび資料
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Datasheet download
参考文献 (8)
ab70808 は 8 報の論文で使用されています。
- Chen X et al. Entorhinal cortex-based metabolic profiling of chronic restraint stress mice model of depression. Aging (Albany NY) 12:3042-3052 (2020). PubMed: 32074509
- Huang ZH et al. Distribution of tyrosine-hydroxylase-immunoreactive neurons in the hypothalamus of tree shrews. J Comp Neurol 528:935-952 (2020). PubMed: 31674014
- Xu K et al. Validation of the targeted metabolomic pathway in the hippocampus and comparative analysis with the prefrontal cortex of social defeat model mice. J Neurochem 149:799-810 (2019). PubMed: 30520040
- Zhou R et al. Baicalin regulates the dopamine system to control the core symptoms of ADHD. Mol Brain 12:11 (2019). PubMed: 30736828
- Iannielli A et al. Reconstitution of the Human Nigro-striatal Pathway on-a-Chip Reveals OPA1-Dependent Mitochondrial Defects and Loss of Dopaminergic Synapses. Cell Rep 29:4646-4656.e4 (2019). PubMed: 31875567
- Jichao S et al. Saikosaponin A Alleviates Symptoms of Attention Deficit Hyperactivity Disorder through Downregulation of DAT and Enhancing BDNF Expression in Spontaneous Hypertensive Rats. Evid Based Complement Alternat Med 2017:2695903 (2017). WB . PubMed: 28293263
- Zhou Q et al. Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson's disease. Nat Commun 7:10332 (2016). ICC/IF ; Mouse . PubMed: 26755131
- Fossmark R et al. ECL-cell carcinoids and carcinoma in patients homozygous for an inactivating mutation in the gastric H(+) K(+) ATPase alpha subunit. APMIS 124:561-6 (2016). PubMed: 27150581