Key features and details
- Rabbit polyclonal to Vinexin
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Vinexin 一次抗体 製品一覧
製品の詳細Rabbit polyclonal to Vinexin
アプリケーション適用あり: WB, IHC-Pmore details
Recombinant fragment, corresponding to a region within amino acids 58-263 of Human Vinexin (O60504).
- HepG2 whole cell lysate; Human colon carcinoma tissue.
保存方法Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
Concentration information loading...
精製度Immunogen affinity purified
Our Abpromise guarantee covers the use of ab126986 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 75 kDa.|
|IHC-P||1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
関連性Vinexin is a focal adhesion protein with a sorbin homology (SoHo) domain as well as 3 SH3 domains. It exists as at least three splice variants - alpha, beta and gamma. It is thought to play a key role in cell adhesion, cell spreading and migration and cytoskeletal organisation. It has also been implicated signaling due to its interaction with the extracellular signal-regulated kinase ERK. Binds to vinculin at sites of cell-cell contact.
細胞内局在Localized at cell-extracellular matrix junctions. Both isoforms were localized at focal adhesion and cell-cell adhesion sites, vinexin beta was also found in the nucleus.
- SCAM 1 antibody
- SCAM1 antibody
- SH3 containing adapter molecule 1 antibody