Anti-VE Cadherin 抗体 (ab231227)
Key features and details
- Rabbit polyclonal to VE Cadherin
- Suitable for: WB, IHC-P
- Reacts with: Rat
- Isotype: IgG
製品の概要
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製品名
Anti-VE Cadherin antibody
VE Cadherin 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to VE Cadherin -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Rat -
免疫原
Recombinant fragment (His-tag) corresponding to Rat VE Cadherin aa 50-400. NP_001100877.1. Expressed in E.coli.
Database link: F1M7E5 -
ポジティブ・コントロール
- WB: Recombinant rat VE-cadherin protein; Rat serum. IHC-P: Rat kidney, testis and pancreas tissues.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.011% Proclin 300
Constituents: 55.77% Glycerol (glycerin, glycerine), 44.219% PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
Antigen-specific affinity chromatography followed by Protein A affinity chromatography. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab231227の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 0.5 - 5 µg/ml. Predicted molecular weight: 88 kDa.
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IHC-P |
Use a concentration of 5 - 20 µg/ml.
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特記事項 |
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WB
Use a concentration of 0.5 - 5 µg/ml. Predicted molecular weight: 88 kDa. |
IHC-P
Use a concentration of 5 - 20 µg/ml. |
ターゲット情報
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機能
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. -
組織特異性
Endothelial tissues and brain. -
配列類似性
Contains 5 cadherin domains. -
翻訳後修飾
Phosphorylated on tyrosine residues by KDR/VEGFR-2. Dephosphorylated by PTPRB. -
細胞内局在
Cell junction. Cell membrane. Found at cell-cell boundaries and probably at cell-matrix boundaries. - Information by UniProt
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参照データベース
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別名
- 7B 4 antibody
- 7B4 antibody
- 7B4 antigen antibody
see all
画像
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Formalin-fixed, paraffin-embedded rat pancreas tissue stained for VE cadherin using ab231227 at 20µg/mL in immunohistochemical analysis.
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Formalin-fixed, paraffin-embedded rat testis tissue stained for VE cadherin using ab231227 at 20µg/mL in immunohistochemical analysis.
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Formalin-fixed, paraffin-embedded rat kidney tissue stained for VE cadherin using ab231227 at 20µg/mL in immunohistochemical analysis.
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Anti-VE Cadherin antibody (ab231227) at 5 µg/ml + Rat serum
Predicted band size: 88 kDa -
Anti-VE Cadherin antibody (ab231227) at 5 µg/ml + Recombinant rat VE Cadherin protein
Predicted band size: 88 kDa
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (6)
ab231227 は 6 報の論文で使用されています。
- Gao J et al. The Effect of Qingre Huayu Recipe on Wound Healing after Anal Fistulotomy in Sprague-Dawley Rats. Comput Math Methods Med 2022:9397478 (2022). PubMed: 35495890
- Ma P et al. The Protective Effect of Sulodexide on Acute Lung Injury Induced by a Murine Model of Obstructive Jaundice. Biomed Res Int 2022:8717950 (2022). PubMed: 36060145
- Tian J et al. Dapagliflozin alleviates cardiac fibrosis through suppressing EndMT and fibroblast activation via AMPKa/TGF-ß/Smad signalling in type 2 diabetic rats. J Cell Mol Med 25:7642-7659 (2021). PubMed: 34169635
- Guo Q et al. ZEB2, interacting with MDM2, contributes to the dysfuntion of brain microvascular endothelial cells and brain injury after intracerebral hemorrhage. Cell Cycle 20:1692-1707 (2021). PubMed: 34334113
- Wang T et al. Inhibition of p38 MAPK Mitigates Lung Ischemia Reperfusion Injury by Reducing Blood-Air Barrier Hyperpermeability. Front Pharmacol 11:569251 (2020). PubMed: 33362540
- Tenghao S et al. Keratinocyte Growth Factor-2 Is Protective in Oleic Acid-Induced Acute Lung Injury in Rats. Evid Based Complement Alternat Med 2019:9406580 (2019). PubMed: 31379970