Anti-VAMP2 抗体 (ab3347)
Key features and details
- Rabbit polyclonal to VAMP2
- Suitable for: WB
- Reacts with: Mouse, Rat, Cow, Human
- Isotype: IgG
製品の概要
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製品名
Anti-VAMP2 antibody
VAMP2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to VAMP2 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse, Rat, Cow, Human
交差が予測される動物種: Rhesus monkey -
免疫原
Synthetic peptide corresponding to Rat VAMP2 aa 1-18.
Sequence:MSATAATVPPAAPAGEGG
(Peptide available asab4958) -
特記事項
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Constituents: PBS, 0.1% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
Our Abpromise guarantee covers the use of ab3347 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB | Use at an assay dependent concentration. Detects a band of approximately 19 kDa (predicted molecular weight: 19 kDa). |
ターゲット情報
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機能
Involved in the targeting and/or fusion of transport vesicles to their target membrane. -
組織特異性
Nervous system and skeletal muscle. -
配列類似性
Belongs to the synaptobrevin family.
Contains 1 v-SNARE coiled-coil homology domain. -
細胞内局在
Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Cell junction > synapse > synaptosome. Neuronal synaptic vesicles. - Information by UniProt
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参照データベース
- Entrez Gene: 282116 Cow
- Entrez Gene: 6844 Human
- Entrez Gene: 22318 Mouse
- Entrez Gene: 24803 Rat
- Omim: 185881 Human
- SwissProt: P63027 Human
- SwissProt: P63044 Mouse
- SwissProt: P63045 Rat
see all -
別名
- FLJ11460 antibody
- RATVAMPB antibody
- RATVAMPIR antibody
see all
画像
プロトコール
参考文献 (37)
ab3347 は 37 報の論文で使用されています。
- Kokotos AC et al. Synaptophysin sustains presynaptic performance by preserving vesicular synaptobrevin-II levels. J Neurochem 151:28-37 (2019). PubMed: 31216055
- Brandenburger T et al. MiR-34a is differentially expressed in dorsal root ganglia in a rat model of chronic neuropathic pain. Neurosci Lett 708:134365 (2019). PubMed: 31278961
- Joussain C et al. Botulinum Neurotoxin Light Chains Expressed by Defective Herpes Simplex Virus Type-1 Vectors Cleave SNARE Proteins and Inhibit CGRP Release in Rat Sensory Neurons. Toxins (Basel) 11:N/A (2019). PubMed: 30791373
- Hoffman BU et al. Merkel Cells Activate Sensory Neural Pathways through Adrenergic Synapses. Neuron 100:1401-1413.e6 (2018). PubMed: 30415995
- Actis Dato V et al. Insulin-induced exocytosis regulates the cell surface level of low-density lipoprotein-related protein-1 in Müller Glial cells. Biochem J 475:1669-1685 (2018). PubMed: 29669912