Anti-uPA Receptor/U-PAR 抗体 (ab3129)
Key features and details
- Goat polyclonal to uPA Receptor/U-PAR
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-uPA Receptor/U-PAR antibody
uPA Receptor/U-PAR 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to uPA Receptor/U-PAR -
由来種
Goat -
種交差性
交差種: Human -
免疫原
Recombinant full length protein corresponding to Human uPA Receptor/U-PAR.
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特記事項
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
Constituents: PBS, 50% Glycerol, 1% BSA -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
ターゲット情報
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機能
Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. -
組織特異性
Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain. -
配列類似性
Contains 3 UPAR/Ly6 domains. -
細胞内局在
Secreted and Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 5329 Human
- Omim: 173391 Human
- SwissProt: Q03405 Human
- Unigene: 466871 Human
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別名
- CD 87 antibody
- CD87 antibody
- CD87 antigen antibody
see all
データシートおよび資料
参考文献 (3)
ab3129 は 3 報の論文で使用されています。
- Pavet V et al. Plasminogen activator urokinase expression reveals TRAIL responsiveness and supports fractional survival of cancer cells. Cell Death Dis 5:e1043 (2014). WB . PubMed: 24481457
- Al-Souhibani N et al. The RNA-binding zinc-finger protein tristetraprolin regulates AU-rich mRNAs involved in breast cancer-related processes. Oncogene : (2010). WB ; Human . PubMed: 20498646
- Bezuidenhout L et al. Ang-2 and PDGF-BB cooperatively stimulate human peripheral blood monocyte fibrinolysis. J Leukoc Biol 81:1496-503 (2007). Neutralising ; Human . PubMed: 17395886