Anti-uPA Receptor/U-PAR 抗体 (ab3129)
Key features and details
- Goat polyclonal to uPA Receptor/U-PAR
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-uPA Receptor/U-PAR antibody
uPA Receptor/U-PAR 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to uPA Receptor/U-PAR -
由来種
Goat -
種交差性
交差種: Human -
免疫原
Recombinant full length protein corresponding to Human uPA Receptor/U-PAR.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
Constituents: PBS, 50% Glycerol, 1% BSA -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
ターゲット情報
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機能
Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. -
組織特異性
Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain. -
配列類似性
Contains 3 UPAR/Ly6 domains. -
細胞内局在
Secreted and Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 5329 Human
- Omim: 173391 Human
- SwissProt: Q03405 Human
- Unigene: 466871 Human
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別名
- CD 87 antibody
- CD87 antibody
- CD87 antigen antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab3129 は 4 報の論文で使用されています。
- Chang J et al. Identification of Two Forms of Human Plasma Renalase, and Their Association With All-Cause Mortality. Kidney Int Rep 5:362-368 (2020). PubMed: 32154458
- Pavet V et al. Plasminogen activator urokinase expression reveals TRAIL responsiveness and supports fractional survival of cancer cells. Cell Death Dis 5:e1043 (2014). WB . PubMed: 24481457
- Al-Souhibani N et al. The RNA-binding zinc-finger protein tristetraprolin regulates AU-rich mRNAs involved in breast cancer-related processes. Oncogene : (2010). WB ; Human . PubMed: 20498646
- Bezuidenhout L et al. Ang-2 and PDGF-BB cooperatively stimulate human peripheral blood monocyte fibrinolysis. J Leukoc Biol 81:1496-503 (2007). Neutralising ; Human . PubMed: 17395886