Anti-UL42 抗体 [2H4] (ab19311)
Key features and details
- Mouse monoclonal [2H4] to UL42
- Suitable for: IP, ELISA, IHC-Fr, WB, ICC/IF
- Reacts with: Species independent
- Isotype: IgG1
製品の概要
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製品名
Anti-UL42 antibody [2H4]
UL42 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [2H4] to UL42 -
由来種
Mouse -
特異性
2H4 will recognise UL42 bound to HSV polymerase. -
アプリケーション
適用あり: IP, ELISA, IHC-Fr, WB, ICC/IFmore details -
種交差性
交差種: Species independent -
免疫原
Baculovirus-expressed HSV DNA polymerase (POL) and POL/UL42 complex.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Constituent: PBS -
Concentration information loading... -
精製度
Protein A/G purified -
ポリ/モノ
モノクローナル -
クローン名
2H4 -
ミエローマ
Sp2/0 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab19311の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IP | ||
| ELISA | ||
| IHC-Fr | ||
| WB | ||
| ICC/IF |
| 特記事項 |
|---|
ICC/IF: Use at an assay dependent dilution PMID 17553899.
IHC-Fr: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 13.6 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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関連性
UL42 is the DNA polymerase accessory protein of herpes simplex virus type 1. -
細胞内局在
Nuclear -
別名
- HHV1gp061 antibody
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (5)
ab19311 は 5 報の論文で使用されています。
- Harancher MR et al. Antiviral Properties of the LSD1 Inhibitor SP-2509. J Virol 94:N/A (2020). PubMed: 32699090
- Döhner K et al. Importin a1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons. PLoS Pathog 14:e1006823 (2018). PubMed: 29304174
- Lv C et al. Ivermectin inhibits DNA polymerase UL42 of pseudorabies virus entrance into the nucleus and proliferation of the virus in vitro and vivo. Antiviral Res 159:55-62 (2018). PubMed: 30266338
- Dembowski JA et al. Replication-Coupled Recruitment of Viral and Cellular Factors to Herpes Simplex Virus Type 1 Replication Forks for the Maintenance and Expression of Viral Genomes. PLoS Pathog 13:e1006166 (2017). PubMed: 28095497
- Chen Y et al. A mutation in the human herpes simplex virus type 1 UL52 zinc finger motif results in defective primase activity but can recruit viral polymerase and support viral replication efficiently. J Virol 81:8742-51 (2007). WB, ICC/IF . PubMed: 17553899
