UDP sodium salt (Uridine 5'-diphosphate), P2Y6 agonist. P2Y14 ligand. (ab120383)

製品の概要

  • 製品名

    UDP sodium salt (Uridine 5'-diphosphate), P2Y6 agonist. P2Y14 ligand.
  • 製品の詳細

    P2Y6 agonist. P2Y14 ligand.
  • 別名

    • Uridine 5'-diphosphate
  • 生理活性の詳細

    Endogenous P2Y receptor agonist which preferentially activates P2Y6. Antagonist and agonist activities reported at human P2Y14 receptors. Potent full agonist at rat P2Y12 (EC50 = 350 nM).
  • 精製度

    > 98%
  • CAS 番号

    21931-53-3
  • 構造式

    Chemical Structure

製品の特性

参考文献

This product has been referenced in:

  • Carter RL  et al. Quantification of Gi-mediated inhibition of adenylyl cyclase activity reveals that UDP is a potent agonist of the human P2Y14 receptor. Mol Pharmacol 76:1341-8 (2009). Read more (PubMed: 19759354) »
  • Fricks IP  et al. UDP is a competitive antagonist at the human P2Y14 receptor. J Pharmacol Exp Ther 325:588-94 (2008). Read more (PubMed: 18252808) »
  • Nicholas RA  et al. Uridine nucleotide selectivity of three phospholipase C-activating P2 receptors: identification of a UDP-selective, a UTP-selective, and an ATP- and UTP-specific receptor. Mol Pharmacol 50:224-9 (1996). Read more (PubMed: 8700127) »

レビューと Q&A

Question
Answer

Thank you for contacting us regarding the extinction coefficient of ab120383.

We don’t measure this data ourselves but a search of available information has pulled up the following:

absorbance max: 262 nm (pH 7)

ε at absorbance max: 9.8 mmol-1 cm-1

We can’t verify that these numbers are correct specifically for ab120383, so use this information at your own discretion.

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