U-18666A, cholesterol transport inhibitor (ab269882)
Key features and details
- Inhibitor of cholesterol synthesis and cellular transport
- CAS Number: 3039-71-2
- Soluble in DMSO to 50 mM and in water to 50 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
U-18666A, cholesterol transport inhibitor -
製品の詳細
Inhibitor of cholesterol synthesis and cellular transport -
生理活性の詳細
Inhibitor of cholesterol synthesis and cellular transport. Impairs intracellular transport of LDL-derived cholesterol in CHO cells. Blocks the ability of LDL-derived cholesterol to suppress HMG-CoA reductase and LDL receptor activity. Weak inhibitor of Hedgehog signaling. Modulates APP cleavage in cultured cells. Tool compound for studying Niemann-Pick disease.
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CAS 番号
3039-71-2 -
構造式
製品の特性
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体系名
(3β)-3-[2-(Diethylamino)ethoxy]-androst-5-en-17-one, hydrochloride -
分子量
424.07 -
分子式
C25H41NO2.HCl -
PubChem 登録番号
9954082 -
保存方法
Shipped at Room Temperature. Store at Room Temperature. Store under desiccating conditions. -
溶解性
Soluble in DMSO to 50 mM and in water to 50 mM -
使用に関する注意
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CCN(CC)CCO[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3CC=C2C1)CCC4=O)C)C.Cl -
由来
Synthetic
関連製品
画像
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab269882 は論文での使用が確認できていません。