Tryptanthrin, immunomodulator (ab269884)
Key features and details
- Indoloquinazoline alkaloid with broad pharmacological activity
- CAS Number: 13220-57-0
- Soluble in DMSO to 100 mM
- Form / State: Solid
製品の概要
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製品名
Tryptanthrin, immunomodulator -
製品の詳細
Indoloquinazoline alkaloid with broad pharmacological activity -
生理活性の詳細
Indoloquinazoline alkaloid with broad pharmacological activity. Immunomodulatory activity. Blocks BV2 microglia activation in response to LPS. Inhibits pro-inflammatory cytockine production via Nrf2, HO-1 and NFκB pathways. Inhibits indoleamine 2,3-dioxygenase 2 (IC50 = 5-17 μM). Promotes neuronal differentiation of human neuroblastoma cells. Also reported to have anti-cancer, anti-microbial and anti-oxidant activity.
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CAS 番号
13220-57-0 -
構造式
製品の特性
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体系名
Indolo[2,1-b]quinazoline-6,12-dione -
分子量
248.24 -
分子式
C15H8N2O2 -
PubChem 登録番号
73549 -
保存方法
Shipped at Room Temperature. Store at -20°C. Store under desiccating conditions. -
溶解性
Soluble in DMSO to 100 mM -
使用に関する注意
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
C1=CC=C2C(=C1)C(=O)N3C4=CC=CC=C4C(=O)C3=N2
画像
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Chemical Structure - Tryptanthrin, immunomodulator (ab269884)
Chemical structure of Tryptanthrin, immunomodulator, 13220-57-0
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (0)
ab269884 は論文での使用が確認できていません。
