Anti-TRAP alpha/TRAPA 抗体 [EPR5604] (ab126775)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR5604] to TRAP alpha/TRAPA
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
製品の概要
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製品名
Anti-TRAP alpha/TRAPA antibody [EPR5604]
TRAP alpha/TRAPA 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR5604] to TRAP alpha/TRAPA -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details
適用なし: Flow Cyt,ICC/IF,IHC-P or IP -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat -
免疫原
Synthetic peptide within Human TRAP alpha/TRAPA aa 250 to the C-terminus (C terminal). The exact sequence is proprietary.
Database link: P43307 -
ポジティブ・コントロール
- HL60 and HepG2 cell lysates.
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
解離定数(KD 値)
KD = 3.30 x 10 -11 M Learn more about KD -
バッファー
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
EPR5604 -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab126775の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
1/1000 - 1/10000. Detects a band of approximately 34 kDa (predicted molecular weight: 32 kDa).
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特記事項 |
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WB
1/1000 - 1/10000. Detects a band of approximately 34 kDa (predicted molecular weight: 32 kDa). |
ターゲット情報
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機能
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins. -
配列類似性
Belongs to the TRAP-alpha family. -
ドメイン
Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged. -
細胞内局在
Endoplasmic reticulum membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 6745 Human
- Entrez Gene: 107513 Mouse
- Entrez Gene: 361233 Rat
- Omim: 600868 Human
- SwissProt: P43307 Human
- SwissProt: Q9CY50 Mouse
- SwissProt: Q7TPJ0 Rat
- Unigene: 114033 Human
see all -
別名
- DKFZp781N23103 antibody
- FLJ14232 antibody
- FLJ22100 antibody
see all
画像
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All lanes : Anti-TRAP alpha/TRAPA antibody [EPR5604] (ab126775) at 1/1000 dilution
Lane 1 : HL60 cell lysate
Lane 2 : HepG2 cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat anti-Rabbit HRP at 1/2000 dilution
Predicted band size: 32 kDa
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab126775 は 2 報の論文で使用されています。
- Zhou L et al. MicroRNA-100-5p inhibits osteoclastogenesis and bone resorption by regulating fibroblast growth factor 21. Int J Mol Med 43:727-738 (2019). PubMed: 30535435
- Wang Y et al. LncRNA LINC00311 Promotes the Proliferation and Differentiation of Osteoclasts in Osteoporotic Rats Through the Notch Signaling Pathway by Targeting DLL3. Cell Physiol Biochem 47:2291-2306 (2018). PubMed: 29975944