Anti-TMPRSS11D 抗体 (ab127031)
Key features and details
- Rabbit polyclonal to TMPRSS11D
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-TMPRSS11D antibody
TMPRSS11D 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to TMPRSS11D -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Recombinant fragment, corresponding to a region within amino acids 152-348 of Human TMPRSS11D (UniProt O60235).
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ポジティブ・コントロール
- HepG2 whole cell lysate (ab7900); Human breast carcinoma tissue
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特記事項
Store undiluted.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab127031の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 46 kDa.
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IHC-P |
1/100 - 1/500. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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特記事項 |
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WB
1/500 - 1/3000. Predicted molecular weight: 46 kDa. |
IHC-P
1/100 - 1/500. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
ターゲット情報
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機能
May play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. -
組織特異性
Located in the cells of the submucosal serous glands of the bronchi and trachea. -
配列類似性
Belongs to the peptidase S1 family.
Contains 1 peptidase S1 domain.
Contains 1 SEA domain. -
細胞内局在
Secreted. Activated by cleavage and secreted and Cell membrane. Activated by cleavage and secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 9407 Human
- Omim: 605369 Human
- SwissProt: O60235 Human
- Unigene: 132195 Human
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別名
- Airway trypsin like protease antibody
- Airway trypsin-like protease antibody
- HAT antibody
see all
画像
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (7)
ab127031 は 7 報の論文で使用されています。
- Hou X et al. 3D-SeboSkin Model for Human ex vivo Studies of Hidradenitis Suppurativa/Acne Inversa. Dermatology 238:236-243 (2022). PubMed: 34077928
- Myti D et al. Elevated FiO2 increases SARS-CoV-2 co-receptor expression in respiratory tract epithelium. Am J Physiol Lung Cell Mol Physiol 319:L670-L674 (2020). PubMed: 32878480
- Zouboulis CC et al. Alterations in innate immunity and epithelial cell differentiation are the molecular pillars of hidradenitis suppurativa. J Eur Acad Dermatol Venereol 34:846-861 (2020). PubMed: 31838778
- Yan K et al. Retracted Article: Knockdown of TMPRSS11D inhibits the proliferation, migration and invasion of cervical cancer cells. RSC Adv 9:21591-21600 (2019). PubMed: 35521321
- Muytjens CMJ et al. Functional proteomic profiling reveals KLK13 and TMPRSS11D as active proteases in the lower female reproductive tract. F1000Res 7:1666 (2018). PubMed: 30647911
- Cao X et al. High TMPRSS11D protein expression predicts poor overall survival in non-small cell lung cancer. Oncotarget 8:12812-12819 (2017). PubMed: 28086212
- Duhaime MJ et al. Cell Surface Human Airway Trypsin-Like Protease Is Lost During Squamous Cell Carcinogenesis. J Cell Physiol 231:1476-83 (2016). PubMed: 26297835