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ab13556 は 98 報の論文で使用されています。

  • Zhao J  et al. B7-H3 is regulated by BRD4 and promotes TLR4 expression in pancreatic ductal adenocarcinoma. Int J Biochem Cell Biol 108:84-91 (2019). PubMed: 30664982
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  • Huang K  et al. Glabridin Prevents Doxorubicin-Induced Cardiotoxicity Through Gut Microbiota Modulation and Colonic Macrophage Polarization in Mice. Front Pharmacol 10:107 (2019). PubMed: 30833897
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  • Cai J  et al. Recombinant fimbriae protein of Porphyromonas gingivalis induces an inflammatory response via the TLR4/NF-?B signaling pathway in human peripheral blood mononuclear cells. Int J Mol Med 43:1430-1440 (2019). PubMed: 30664173
  • Wu J  et al. Impact of miR-223-3p and miR-2909 on inflammatory factors IL-6, IL-1ß, and TNF-a, and the TLR4/TLR2/NF-?B/STAT3 signaling pathway induced by lipopolysaccharide in human adipose stem cells. PLoS One 14:e0212063 (2019). PubMed: 30807577
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  • Yang WS  et al. Ectodomain Shedding of RAGE and TLR4 as a Negative Feedback Regulation in High-Mobility Group Box 1-Activated Aortic Endothelial Cells. Cell Physiol Biochem 51:1632-1644 (2018). PubMed: 30497069
  • Xiong G  et al. Clethodim exposure induces developmental immunotoxicity and neurobehavioral dysfunction in zebrafish embryos. Fish Shellfish Immunol 86:549-558 (2018). PubMed: 30517881
  • Peng JH  et al. Geniposide and Chlorogenic Acid Combination Ameliorates Non-alcoholic Steatohepatitis Involving the Protection on the Gut Barrier Function in Mouse Induced by High-Fat Diet. Front Pharmacol 9:1399 (2018). PubMed: 30618733
  • Xu M  et al. MicroRNA-34a Inhibition of the TLR Signaling Pathway Via CXCL10 Suppresses Breast Cancer Cell Invasion and Migration. Cell Physiol Biochem 46:1286-1304 (2018). PubMed: 29689563
  • Wang W & Wang J Toll-Like Receptor 4 (TLR4)/Cyclooxygenase-2 (COX-2) Regulates Prostate Cancer Cell Proliferation, Migration, and Invasion by NF-?B Activation. Med Sci Monit 24:5588-5597 (2018). PubMed: 30098292
  • Shao L  et al. The impact of exogenous CO releasing molecule CORM-2 on inflammation and signaling of orthotopic lung cancer. Oncol Lett 16:3223-3230 (2018). PubMed: 30127918
  • Liu W  et al. Ulinastatin protects the lungs of COPD rats through the HMGB1/TLR4 signaling pathway. Oncol Lett 16:4057-4063 (2018). PubMed: 30128028
  • Wu H  et al. Anti-Inflammatory Effect of a Polyphenol-Enriched Fraction from Acalypha wilkesiana on Lipopolysaccharide-Stimulated RAW 264.7 Macrophages and Acetaminophen-Induced Liver Injury in Mice. Oxid Med Cell Longev 2018:7858094 (2018). PubMed: 30159118
  • Sun Y  et al. Exercise intervention alleviates nerve injury by the suppression of inflammatory mediator expression via the TLR4/NF-?B signaling pathway. Exp Ther Med 16:2922-2930 (2018). PubMed: 30233666
  • Sun Y  et al. Aflatoxin B1 Promotes Influenza Replication and Increases Virus Related Lung Damage via Activation of TLR4 Signaling. Front Immunol 9:2297 (2018). PubMed: 30337931
  • Zhou ZX  et al. Anti-inflammatory activity of resveratrol prevents inflammation by inhibiting NF-?B in animal models of acute pharyngitis. Mol Med Rep 17:1269-1274 (2018). PubMed: 29115472
  • Tang KC  et al. Effect of miR-495 on lower extremity deep vein thrombosis through the TLR4 signaling pathway by regulation of IL1R1. Biosci Rep 38:N/A (2018). PubMed: 30287499
  • Liu Y  et al. Lentiviral-mediated inducible silencing of TLR4 attenuates neuropathic pain in a rat model of chronic constriction injury. Mol Med Rep 18:5545-5551 (2018). PubMed: 30365084
  • Latorre E  et al. Toll-like receptors 2 and 4 modulate intestinal IL-10 differently in ileum and colon. United European Gastroenterol J 6:446-453 (2018). PubMed: 29774159
  • Yu L  et al. LncRNA-PCAT1 targeting miR-145-5p promotes TLR4-associated osteogenic differentiation of adipose-derived stem cells. J Cell Mol Med 22:6134-6147 (2018). PubMed: 30338912
  • Wu XJ  et al. Penehyclidine hydrochloride inhibits TLR4 signaling and inflammation, and attenuates blunt chest trauma and hemorrhagic shock-induced acute lung injury in rats. Mol Med Rep 17:6327-6336 (2018). PubMed: 29488614
  • Cao W  et al. Homeobox a5 Promotes White Adipose Tissue Browning Through Inhibition of the Tenascin C/Toll-Like Receptor 4/Nuclear Factor Kappa B Inflammatory Signaling in Mice. Front Immunol 9:647 (2018). PubMed: 29651293
  • Alhasson F  et al. High circulatory leptin mediated NOX-2-peroxynitrite-miR21 axis activate mesangial cells and promotes renal inflammatory pathology in nonalcoholic fatty liver disease. Redox Biol 17:1-15 (2018). IHC-P ; Mouse . PubMed: 29660503
  • Jia J  et al. Cholesterol metabolism promotes B-cell positioning during immune pathogenesis of chronic obstructive pulmonary disease. EMBO Mol Med 10:N/A (2018). PubMed: 29674392
  • Wang Y  et al. Sparstolonin B improves neurological outcomes following intracerebral hemorrhage in mice. Exp Ther Med 15:5436-5442 (2018). PubMed: 29844805
  • Zhu H  et al. Houttuynia cordata polysaccharides ameliorate pneumonia severity and intestinal injury in mice with influenza virus infection. J Ethnopharmacol 218:90-99 (2018). PubMed: 29471085
  • Liu Y  et al. Breviscapine ameliorates CCl4-induced liver injury in mice through inhibiting inflammatory apoptotic response and ROS generation. Int J Mol Med 42:755-768 (2018). PubMed: 29717768
  • Kang Y  et al. Activation of the TLR4/MyD88 signaling pathway contributes to the development of human hepatocellular carcinoma via upregulation of IL-23 and IL-17A. Oncol Lett 15:9647-9654 (2018). PubMed: 29928340
  • Sauter MM  et al. Toll-like receptors 4, 5, 6 and 7 are constitutively expressed in non-human primate retinal neurons. J Neuroimmunol 322:26-35 (2018). PubMed: 29954626
  • Gao W  et al. IL-2/Anti-IL-2 Complex Attenuates Inflammation and BBB Disruption in Mice Subjected to Traumatic Brain Injury. Front Neurol 8:281 (2017). PubMed: 28713327
  • Jiang C  et al. The Expression of Toll-like receptors in eutopic and ectopic endometrium and its implication in the inflammatory pathogenesis of adenomyosis. Sci Rep 7:7365 (2017). PubMed: 28779087
  • Wu R  et al. Effects of Tim-3 silencing on the viability of fibroblast-like synoviocytes and lipopolysaccharide-induced inflammatory reactions. Exp Ther Med 14:2721-2727 (2017). PubMed: 28962218
  • Wang S  et al. Establishment of a mouse model of lipopolysaccharide-induced neutrophilic nasal polyps. Exp Ther Med 14:5275-5282 (2017). PubMed: 29285053
  • Ji D  et al. Anti-nociceptive effect of dexmedetomidine in a rat model of monoarthritis via suppression of the TLR4/NF-?B p65 pathway. Exp Ther Med 14:4910-4918 (2017). PubMed: 29201195
  • Luo X  et al. Baicalein ameliorates TNBS-induced colitis by suppressing TLR4/MyD88 signaling cascade and NLRP3 inflammasome activation in mice. Sci Rep 7:16374 (2017). PubMed: 29180692
  • Zhou ZQ  et al. Role of ESAT-6 in renal injury by regulating microRNA-155 expression via TLR4/MyD88 signaling pathway in mice withMycobacterium tuberculosisinfection. Biosci Rep 37:N/A (2017). PubMed: 28655852
  • Yu T  et al. Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy. Cell 170:548-563.e16 (2017). PubMed: 28753429
  • Du M  et al. The LPS-inducible lncRNA Mirt2 is a negative regulator of inflammation. Nat Commun 8:2049 (2017). WB . PubMed: 29230038
  • Liu Q  et al. C1q/TNF-related protein 9 inhibits the cholesterol-induced Vascular smooth muscle cell phenotype switch and cell dysfunction by activating AMP-dependent kinase. J Cell Mol Med 21:2823-2836 (2017). PubMed: 28524645
  • Xu X  et al. MicroRNA-1906, a Novel Regulator of Toll-Like Receptor 4, Ameliorates Ischemic Injury after Experimental Stroke in Mice. J Neurosci 37:10498-10515 (2017). PubMed: 28924010
  • Zhang H  et al. Toll-Like Receptor 4-Myeloid Differentiation Primary Response Gene 88 Pathway Is Involved in the Inflammatory Development of Polymyositis by Mediating Interferon-? and Interleukin-17A in Humans and Experimental Autoimmune Myositis Mouse Model. Front Neurol 8:132 (2017). IHC-P . PubMed: 28446897
  • Shen W  et al. High mobility group box 1 induces calcification of aortic valve interstitial cells via toll-like receptor 4. Mol Med Rep 15:2530-2536 (2017). IHC-Fr ; Human . PubMed: 28260034
  • Tang HL  et al. Toll-Like Receptor 4 in Paraventricular Nucleus Mediates Visceral Hypersensitivity Induced by Maternal Separation. Front Pharmacol 8:309 (2017). ICC/IF ; Mouse . PubMed: 28611665
  • Xue X  et al. Immunoregulatory Role of MicroRNA-21 in Macrophages in Response to Bacillus Calmette-Guerin Infection Involves Modulation of the TLR4/MyD88 Signaling Pathway. Cell Physiol Biochem 42:91-102 (2017). PubMed: 28494464
  • Zeng XY  et al. Forsythoside A exerts an anti-endotoxin effect by blocking the LPS/TLR4 signaling pathway and inhibiting Tregs in vitro. Int J Mol Med 40:243-250 (2017). PubMed: 28534936
  • Luo ZL  et al. The Role of Exogenous Hydrogen Sulfide in Free Fatty Acids Induced Inflammation in Macrophages. Cell Physiol Biochem 42:1635-1644 (2017). PubMed: 28738323
  • Zhu JW  et al. Toll-Like Receptor 4 Deficiency Impairs Motor Coordination. Front Neurosci 10:33 (2016). IHC-Fr ; Mouse . PubMed: 26909014
  • Zou Y  et al. sTLR4/MD-2 complex inhibits colorectal cancer in vitro and in vivo by targeting LPS. Oncotarget 7:52032-52044 (2016). IHC . PubMed: 27409669
  • Yuan J  et al. Ferulic acid attenuated acetaminophen-induced hepatotoxicity though down-regulating the cytochrome P 2E1 and inhibiting toll-like receptor 4 signaling-mediated inflammation in mice. Am J Transl Res 8:4205-4214 (2016). PubMed: 27830004
  • Zhu Z  et al. Inhibitory Effect of TLR4 Gene Silencing on Intimal Hyperplasia of Vein Grafting. Vasc Endovascular Surg 50:464-469 (2016). PubMed: 27681173
  • Li X  et al. Quercetin attenuates the activation of hepatic stellate cells and liver fibrosis in mice through modulation of HMGB1-TLR2/4-NF-?B signaling pathways. Toxicol Lett 261:1-12 (2016). PubMed: 27601294
  • Lai CH  et al. Toll-Like Receptor 4 Is Essential in the Development of Abdominal Aortic Aneurysm. PLoS One 11:e0146565 (2016). PubMed: 26741694
  • Honda S  et al. Marginal zone B cells exacerbate endotoxic shock via interleukin-6 secretion induced by Fca/µR-coupled TLR4 signalling. Nat Commun 7:11498 (2016). ICC/IF . PubMed: 27146354
  • Siemieniuch MJ  et al. Type of Inflammation Differentially Affects Expression of Interleukin 1ß and 6, Tumor Necrosis Factor-a and Toll-Like Receptors in Subclinical Endometritis in Mares. PLoS One 11:e0154934 (2016). PubMed: 27152525
  • Du J  et al. TLR4-dependent signaling pathway modulation: A novel mechanism by which pioglitazone protects against nutritional fibrotic steatohepatitis in mice. Mol Med Rep 13:2159-66 (2016). PubMed: 26781175
  • Noh EJ  et al. Withaferin A inhibits inflammatory responses induced by Fusobacterium nucleatum and Aggregatibacter actinomycetemcomitans in macrophages. Mol Med Rep 14:983-8 (2016). PubMed: 27220676
  • Vethanayagam RR  et al. Toll-like receptor 4 modulates the cochlear immune response to acoustic injury. Cell Death Dis 7:e2245 (2016). PubMed: 27253409
  • Reis WL  et al. Brain innate immunity regulates hypothalamic arcuate neuronal activity and feeding behavior. Endocrinology 156:1303-15 (2015). PubMed: 25646713
  • Wang C  et al. Pterostilbene attenuates inflammation in rat heart subjected to ischemia-reperfusion: role of TLR4/NF-?B signaling pathway. Int J Clin Exp Med 8:1737-46 (2015). Rat . PubMed: 25932102
  • Ulbrich F  et al. Argon Mediates Anti-Apoptotic Signaling and Neuroprotection via Inhibition of Toll-Like Receptor 2 and 4. PLoS One 10:e0143887 (2015). WB ; Human . PubMed: 26624894
  • Ouyang Q  et al. Apolipoprotein E deficiency and high-fat diet cooperate to trigger lipidosis and inflammation in the lung via the toll-like receptor 4 pathway. Mol Med Rep 12:2589-97 (2015). WB, IHC ; Mouse . PubMed: 25975841
  • Li J  et al. Resveratrol attenuates inflammation in the rat heart subjected to ischemia-reperfusion: Role of the TLR4/NF-?B signaling pathway. Mol Med Rep 11:1120-6 (2015). PubMed: 25405531
  • Dange RB  et al. Toll-like receptor 4 inhibition within the paraventricular nucleus attenuates blood pressure and inflammatory response in a genetic model of hypertension. J Neuroinflammation 12:31 (2015). IF . PubMed: 25879545
  • Lin JJ  et al. Toll-like receptor 4 signaling in neurons of trigeminal ganglion contributes to nociception induced by acute pulpitis in rats. Sci Rep 5:12549 (2015). WB ; Rat . PubMed: 26224622
  • Masson GS  et al. Toll-like receptor 4 promotes autonomic dysfunction, inflammation and microglia activation in the hypothalamic paraventricular nucleus: role of endoplasmic reticulum stress. PLoS One 10:e0122850 (2015). IF ; Rat . PubMed: 25811788
  • Ilievski V  et al. TLR4 Expression by Liver Resident Cells Mediates the Development of Glucose Intolerance and Insulin Resistance in Experimental Periodontitis. PLoS One 10:e0136502 (2015). IF ; Mouse . PubMed: 26317345
  • Shin WH  et al. Induction of microglial toll-like receptor 4 by prothrombin kringle-2: a potential pathogenic mechanism in Parkinson's disease. Sci Rep 5:14764 (2015). PubMed: 26440368
  • Djikic J  et al. Age-associated changes in rat immune system: Lessons learned from experimental autoimmune encephalomyelitis. Exp Gerontol 58C:179-197 (2014). Rat . PubMed: 25128713
  • Faria MS  et al. Role of protein kinase R in the killing of Leishmania major by macrophages in response to neutrophil elastase and TLR4 via TNFa and IFNß. FASEB J 28:3050-63 (2014). Mouse . PubMed: 24732131
  • Cai Q  et al. Molecular profile of cochlear immunity in the resident cells of the organ of Corti. J Neuroinflammation 11:173 (2014). WB ; Mouse . PubMed: 25311735
  • Xia Y  et al. Influenza vaccination during early pregnancy contributes to neurogenesis and behavioral function in offspring. Brain Behav Immun 42:212-21 (2014). ICC/IF ; Mouse . PubMed: 25014010
  • Qian H  et al. Sophocarpine attenuates liver fibrosis by inhibiting the TLR4 signaling pathway in rats. World J Gastroenterol 20:1822-32 (2014). WB, IHC ; Rat . PubMed: 24587659
  • Li Y  et al. Toll-like receptor 4 signaling contributes to Paclitaxel-induced peripheral neuropathy. J Pain 15:712-25 (2014). ICC/IF . PubMed: 24755282
  • Ingham V  et al. Glimepiride reduces CD14 expression and cytokine secretion from macrophages. J Neuroinflammation 11:115 (2014). ELISA ; Mouse . PubMed: 24952384
  • Wilson CB  et al. Differential effects of sertraline in a predator exposure animal model of post-traumatic stress disorder. Front Behav Neurosci 8:256 (2014). PubMed: 25126063
  • Wilson BJ  et al. ABCB5 maintains melanoma-initiating cells through a proinflammatory cytokine signaling circuit. Cancer Res 74:4196-207 (2014). PubMed: 24934811
  • Shang T  et al. Tanshinone IIA attenuates elastase-induced AAA in rats via inhibition of MyD88-dependent TLR-4 signaling. Vasa 43:39-46 (2014). PubMed: 24429329
  • Hiratsuka S  et al. Primary tumours modulate innate immune signalling to create pre-metastatic vascular hyperpermeability foci. Nat Commun 4:1853 (2013). Mouse . PubMed: 23673638
  • Gu H  et al. Necro-inflammatory response of pancreatic acinar cells in the pathogenesis of acute alcoholic pancreatitis. Cell Death Dis 4:e816 (2013). Rat . PubMed: 24091659
  • Fernandez I  et al. Functional redundancy of MyD88-dependent signaling pathways in a murine model of histidyl-transfer RNA synthetase-induced myositis. J Immunol 191:1865-72 (2013). IHC . PubMed: 23842751
  • Rabadi MM  et al. Interaction between uric acid and HMGB1 translocation and release from endothelial cells. Am J Physiol Renal Physiol 302:F730-41 (2012). WB ; Human . PubMed: 22189943
  • Good DW  et al. Toll-like Receptor 2 is Required for LPS-induced Toll-like Receptor 4 Signaling and Inhibition of Ion Transport in Renal Thick Ascending Limb. J Biol Chem : (2012). WB, IHC ; Mouse . PubMed: 22523073
  • Ghaly T  et al. Hydrogel-embedded endothelial progenitor cells evade LPS and mitigate endotoxemia. Am J Physiol Renal Physiol 301:F802-12 (2011). ICC/IF, Flow Cyt ; Mouse . PubMed: 21775481
  • Willis LM  et al. Walnut extract inhibits LPS-induced activation of BV-2 microglia via internalization of TLR4: possible involvement of phospholipase D2. Inflammation 33:325-33 (2010). WB ; Mouse . PubMed: 20213499
  • Marchant D  et al. Toll-like receptor 4-mediated activation of p38 mitogen-activated protein kinase is a determinant of respiratory virus entry and tropism. J Virol 84:11359-73 (2010). Human . PubMed: 20702616
  • Kristiansen KA & Edvinsson L Neurogenic inflammation: a study of rat trigeminal ganglion. J Headache Pain 11:485-95 (2010). IHC . PubMed: 20931347
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