Anti-TGF beta 2 抗体 (ab80059)
Key features and details
- Rabbit polyclonal to TGF beta 2
- Suitable for: IHC, WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-TGF beta 2 antibody
TGF beta 2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to TGF beta 2 -
由来種
Rabbit -
特異性
Reacts specifically with human 48 kDa TGF beta 2 protein. -
アプリケーション
適用あり: IHC, WBmore details -
種交差性
交差種: Human
交差が予測される動物種: a wide range of other species -
免疫原
Synthetic peptide derived from the N terminal domain of Human TGF beta 2.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Constituent: Whole serum -
Concentration information loading...
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精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab80059の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC |
1/100 - 1/500.
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WB | (1) |
1/500 - 1/5000. Predicted molecular weight: 47 kDa.
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特記事項 |
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IHC
1/100 - 1/500. |
WB
1/500 - 1/5000. Predicted molecular weight: 47 kDa. |
ターゲット情報
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機能
TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth. -
関連疾患
A chromosomal aberration involving TGFB2 is found in a family with Peters anomaly. Translocation t(1;7)(q41;p21) with HDAC9.
Loeys-Dietz syndrome 4
Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD). NSAD is a frequently asymptomatic but potentially lethal disease characterized by thoracic aortic aneurysms and dissections without additional syndromic features. -
配列類似性
Belongs to the TGF-beta family. -
翻訳後修飾
The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 7040 Human
- Entrez Gene: 7042 Human
- Entrez Gene: 7043 Human
- Omim: 190220 Human
- SwissProt: P01137 Human
- SwissProt: P10600 Human
- SwissProt: P61812 Human
- Unigene: 133379 Human
see all -
別名
- BSC-1 cell growth inhibitor antibody
- BSC1 cell growth inhibitor antibody
- Cetermin antibody
see all
データシートおよび資料
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Datasheet download
参考文献 (2)
ab80059 は 2 報の論文で使用されています。
- Chuo D et al. LncRNA MIR503HG is downregulated in Han Chinese with colorectal cancer and inhibits cell migration and invasion mediated by TGF-ß2. Gene 713:143960 (2019). PubMed: 31278965
- Nicola T et al. Hypoxia-induced inhibition of lung development is attenuated by the peroxisome proliferator-activated receptor-{gamma} agonist rosiglitazone. Am J Physiol Lung Cell Mol Physiol 301:L125-34 (2011). WB ; Mouse . PubMed: 21531777