Anti-TGF beta 2 抗体 (ab167655)
Key features and details
- Mouse polyclonal to TGF beta 2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-TGF beta 2 antibody
TGF beta 2 一次抗体 製品一覧 -
製品の詳細
Mouse polyclonal to TGF beta 2 -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Rabbit, Horse, Cow, Dog, Chimpanzee, Rhesus monkey -
免疫原
Recombinant full length protein, corresponding to amino acids 1-414 of Human TGF beta 2 (AAH99635.1).
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ポジティブ・コントロール
- TGF beta 2 transfected 293T cell lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
pH: 7.4
Constituent: 100% PBS -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab167655の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 48 kDa.
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特記事項 |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 48 kDa. |
ターゲット情報
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機能
TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth. -
関連疾患
A chromosomal aberration involving TGFB2 is found in a family with Peters anomaly. Translocation t(1;7)(q41;p21) with HDAC9.
Loeys-Dietz syndrome 4
Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD). NSAD is a frequently asymptomatic but potentially lethal disease characterized by thoracic aortic aneurysms and dissections without additional syndromic features. -
配列類似性
Belongs to the TGF-beta family. -
翻訳後修飾
The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 534069 Cow
- Entrez Gene: 7040 Human
- Entrez Gene: 7042 Human
- Entrez Gene: 7043 Human
- Entrez Gene: 100009371 Rabbit
- Omim: 190220 Human
- SwissProt: P21214 Cow
- SwissProt: P01137 Human
see all -
別名
- BSC-1 cell growth inhibitor antibody
- BSC1 cell growth inhibitor antibody
- Cetermin antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (3)
ab167655 は 3 報の論文で使用されています。
- Song L et al. Phytosterol esters attenuate hepatic steatosis in rats with non-alcoholic fatty liver disease rats fed a high-fat diet. Sci Rep 7:41604 (2017). WB ; Rat . PubMed: 28169366
- Zhuang R et al. CR6-interacting factor 1 inhibits invasiveness by suppressing TGF-ß-mediated epithelial-mesenchymal transition in hepatocellular carcinoma. Oncotarget 8:94759-94768 (2017). PubMed: 29212264
- Liu Y et al. RUNX3 modulates hypoxia-induced endothelial-to-mesenchymal transition of human cardiac microvascular endothelial cells. Int J Mol Med 40:65-74 (2017). PubMed: 28534977