Key features and details
- Rabbit polyclonal to TGF alpha
- Suitable for: Sandwich ELISA
- Reacts with: Human
- Isotype: unknown
製品名Anti-TGF alpha antibody
TGF alpha 一次抗体 製品一覧
製品の詳細Rabbit polyclonal to TGF alpha
特異性The immunogen shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.
アプリケーション適用あり: Sandwich ELISAmore details
This product is no longer batch tested in IHC, for an IHC validated antibody please see ab208156
製品の状態Lyophilized:Reconstitute with 200µl of sterile water. The reconstituted antibody is stable for at least 2 weeks at 2-8C and at least 6 months at -20C.
保存方法Shipped at 4°C. Store at -20ºC.
Concentration information loading...
精製度Immunogen affinity purified
Immunizing Peptide (Blocking)
Our Abpromise guarantee covers the use of ab9585 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Sandwich ELISA||Use at an assay dependent concentration.
To detect Human TGF-α by sandwich ELISA (using 100 μl/well antibody solution) a concentration of 0.5 - 2.0 μg/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with suitable detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant Human TGF-α.
機能TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.
組織特異性Isoform 1, isoform 3 and isoform 4 are expressed in keratinocytes and tumor-derived cell lines.
配列類似性Contains 1 EGF-like domain.
細胞内局在Cell membrane and Secreted > extracellular space.
- Information by UniProt
- EGF like TGF antibody
- EGF-like TGF antibody
- ETGF antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab9585 は 11 報の論文で使用されています。
- Kibe S et al. Cancer-associated acinar-to-ductal metaplasia within the invasive front of pancreatic cancer contributes to local invasion. Cancer Lett 444:70-81 (2019). PubMed: 30590101
- Li Y et al. Blockage of TGF-a Induced by Spherical Silica Nanoparticles Inhibits Epithelial-Mesenchymal Transition and Proliferation of Human Lung Epithelial Cells. Biomed Res Int 2019:8231267 (2019). PubMed: 30906781
- Mao Y et al. Repair Effects of KGF on Ischemia-Reperfusion-Induced Flap Injury via Activating Nrf2 Signaling. J Surg Res 244:547-557 (2019). PubMed: 31351398
- Romualdo GR et al. Fibrosis-associated hepatocarcinogenesis revisited: Establishing standard medium-term chemically-induced male and female models. PLoS One 13:e0203879 (2018). PubMed: 30212575
- Arnli MB et al. Expression and clinical value of EGFR in human meningiomas. PeerJ 5:e3140 (2017). PubMed: 28367377