製品の概要

  • 製品名

    Tertiapin LQ, Kir1.1 channels blocker
  • 製品の詳細

    Potent, selective blocker of Kir1.1 channels. Tertiapin Q (ab120432) derivative.
  • 生理活性の詳細

    Tertiapin Q (ab120432) derivative. Potent, selective blocker of Kir1.1 channels. Shows greater than >250-fold selectivity for Kir1.1 over Kir3.1/3.4 (Kd values are 1.3 and 274 nM at Kir1.1 and Kir3.1/3.4, respectively). Displays greater selectivity at Kir1.1 than Tertiapin Q (ab120432).
  • 精製度

    > 95%
  • 特記事項

    Sold under license granted by the University of Pennsylvania.
  • 構造式

    Chemical Structure

製品の特性

参考文献

This product has been referenced in:

  • Ramu Y  et al. Engineered specific and high-affinity inhibitor for a subtype of inward-rectifier K+ channels. Proc Natl Acad Sci U S A 105:10774-8 (2008). Read more (PubMed: 18669667) »

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