Anti-TCR V beta 5 抗体 [MEM-262] (ab1898)
製品の概要
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製品名Anti-TCR V beta 5 antibody [MEM-262]
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製品の詳細Mouse monoclonal [MEM-262] to TCR V beta 5
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由来種Mouse
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特異性The antibody recognizes beta chains of the TCR expressed by HPB-ALL cell line [carrying V(beta5.3)] and a small subset of peripheral blood T cells. This subset is larger than that recognized by other V(beta5.3)-specific antibodies.
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アプリケーション適用あり: Flow Cyt, IP, WBmore details
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種交差性交差種: Human
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免疫原
Human thymoma cell line HPB-ALL.
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特記事項Functional Application Activates T cells (V beta 5-related subset).
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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バッファーPreservative: 15mM Sodium Azide
Constituents: PBS, pH 7.4 -
Concentration information loading... -
精製度>95% by SDS-PAGE
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特記事項（精製）Purified from hybridoma culture supernatant by protein A affinity chromatography.
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ポリ/モノモノクローナル
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クローン名MEM-262
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アイソタイプIgG2a
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab1898 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt | ||
| IP | ||
| WB |
追加情報
Flow Cyt: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Uniquely recognizes denatured TCR beta chains under the conditions of Western blotting.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
IP: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Uniquely recognizes denatured TCR beta chains under the conditions of Western blotting.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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関連性T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. The beta locus includes V (variable), J (joining), diversity (D), and C (constant) segments. The Vß5 TCR is a variant of the TCR ß chain. It belongs to Ig superfamily and is expressed by a subset of peripheral blood T cells and some T cell clones. TCR Vß5 has been reported to recognize some staphylococcus bacterial superantigens.
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細胞内局在Cell Membrane
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参照データベース
- Entrez Gene: 28612 Human
- Omim: 186930 Human
- SwissProt: P03979 Human
- SwissProt: P04435 Human
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別名
- T cell receptor antibody
- TCB antibody
- TCRB antibody
see all
参考文献
This product has been referenced in:
- Wang CT et al. Attenuating systemic inflammatory markers in simulated high-altitude exposure by heat shock protein 70-mediated hypobaric hypoxia preconditioning in rats. J Formos Med Assoc 114:328-38 (2015). Read more (PubMed: 25839766) »
- Grabherr MG et al. Exploiting nucleotide composition to engineer promoters. PLoS One 6:e20136 (2011). Read more (PubMed: 21625601) »
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"