TC-2403 oxalate, alpha4beta2 nAChR selective agonist (ab120557)
Key features and details
- Potent α4β2 nAChR selective agonist
- CAS Number: 252870-46-5
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
TC-2403 oxalate, alpha4beta2 nAChR selective agonist -
製品の詳細
Potent α4β2 nAChR selective agonist -
別名
- RJR 2403
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生理活性の詳細
High affinity α4β2 nAChR selective agonist (Ki = 26 nM). Selective for CNS nAChR over muscle, ganglionic or enteric ACh receptors (EC50 = 732 nM in rat thalamic synaptosomes).
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精製度
> 99% -
CAS 番号
252870-46-5 -
構造式
製品の特性
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体系名
(E)-N-Methyl-4-(3-pyridinyl)-3-buten-1-amine oxalate -
分子量
252.27 -
分子式
C10H14N2.C2H2O4 -
保存方法
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in water to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (1)
ab120557 は 1 報の論文で使用されています。
- Grandi A et al. a7 Nicotinic Agonist AR-R17779 Protects Mice against 2,4,6-Trinitrobenzene Sulfonic Acid-Induced Colitis in a Spleen-Dependent Way. Front Pharmacol 8:809 (2017). PubMed: 29167641