Anti-TBL1 抗体 (ab2243)
製品の概要
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製品名
Anti-TBL1 antibody
TBL1 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to TBL1 -
由来種
Goat -
特異性
This antibody is also expected to recognise the human protein TBLR1 (NP_078941), which is very similar. -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Cow, Dog -
免疫原
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ポジティブ・コントロール
- IHC-P: Human kidney tissue.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.05% Tris, 0.5% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Immunizing Peptide (Blocking)
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Isotype control
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Recombinant Protein
アプリケーション
Our Abpromise guarantee covers the use of ab2243 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
アプリケーション | Abreviews | 特記事項 |
---|---|---|
IHC-P | Use a concentration of 4 - 6 µg/ml. |
ターゲット情報
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機能
F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange. -
組織特異性
Ubiquitous. -
配列類似性
Belongs to the WD repeat EBI family.
Contains 1 F-box-like domain.
Contains 1 LisH domain.
Contains 8 WD repeats. -
ドメイン
The F-box-like domain is related to the F-box domain, and apparently displays the same function as component of ubiquitin E3 ligase complexes. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 515972 Cow
- Entrez Gene: 6907 Human
- Entrez Gene: 21372 Mouse
- Entrez Gene: 302711 Rat
- Omim: 300196 Human
- SwissProt: O60907 Human
- SwissProt: Q9QXE7 Mouse
- Unigene: 495656 Human
see all -
別名
- EBI antibody
- F box like/WD repeat protein TBL1X antibody
- F-box-like/WD repeat-containing protein TBL1X antibody
see all
画像
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Immunohistochemical analysis of paraffin embedded Human Kidney tissue labeling TBL1 with ab5642 at 4 ug/ml. Tissue underwent antigen retrieval in steam with Tris/EDTA buffer (pH 9.0). The HRP-staining procedure was used for detection.
データシートおよび資料
参考文献
This product has been referenced in:
- Hoberg JE et al. SMRT derepression by the IkappaB kinase alpha: a prerequisite to NF-kappaB transcription and survival. Mol Cell 16:245-55 (2004). Read more (PubMed: 15494311) »