TBB, casein kinase-2 (CK2) inhibitor (ab120988)
Key features and details
- Selective, cell-permeable casein kinase-2 (CK2) inhibitor
- CAS Number: 17374-26-4
- Purity: > 98%
- Soluble in DMSO to 100 mM and in ethanol to 20 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
TBB, casein kinase-2 (CK2) inhibitor -
製品の詳細
Selective, cell-permeable casein kinase-2 (CK2) inhibitor -
別名
- NSC 231634
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生理活性の詳細
Selective, cell-permeable casein kinase-2 (CK2) inhibitor (IC50 = 0.5 μM). Acts in an ATP/GTP competitive manner. Induces apoptosis.
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精製度
> 98% -
CAS 番号
17374-26-4 -
構造式
製品の特性
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体系名
4,5,6,7-Tetrabromo-1H-benzotriazole -
分子量
434.71 -
分子式
C6HBr4N3 -
PubChem 登録番号
1694 -
保存方法
Store at +4°C. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 100 mM and in ethanol to 20 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
Brc2c1nnnc1c(Br)c(Br)c2Br -
由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (3)
ab120988 は 3 報の論文で使用されています。
- Azad P et al. Long noncoding RNA HIKER regulates erythropoiesis in Monge's disease via CSNK2B. J Clin Invest 133:N/A (2023). PubMed: 37022795
- Sano K et al. Tyrosine 136 phosphorylation of a-synuclein aggregates in the Lewy body dementia brain: involvement of serine 129 phosphorylation by casein kinase 2. Acta Neuropathol Commun 9:182 (2021). PubMed: 34772466
- González N et al. Ck2-Dependent Phosphorylation Is Required to Maintain Pax7 Protein Levels in Proliferating Muscle Progenitors. PLoS One 11:e0154919 (2016). PubMed: 27144531