Anti-Tartrate Resistant Acid Phosphatase 抗体 [ACP5/1070] - BSA and Azide free (ab212723)
Key features and details
- Mouse monoclonal [ACP5/1070] to Tartrate Resistant Acid Phosphatase - BSA and Azide free
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG2b
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Tartrate Resistant Acid Phosphatase antibody [ACP5/1070] - BSA and Azide free
Tartrate Resistant Acid Phosphatase 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [ACP5/1070] to Tartrate Resistant Acid Phosphatase - BSA and Azide free -
由来種
Mouse -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Recombinant full length protein corresponding to Human Tartrate Resistant Acid Phosphatase.
Database link: P13686 -
ポジティブ・コントロール
- Human spleen tissue; HepG2, 293T, K562 or RPMI-8226 cells.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.2
Constituent: 100% PBS -
キャリア・フリー
はい -
Concentration information loading...
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精製度
Protein A/G purified -
ポリ/モノ
モノクローナル -
クローン名
ACP5/1070 -
アイソタイプ
IgG2b -
軽鎖の種類
kappa -
研究分野
関連製品
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Alternative Versions
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Compatible Secondaries
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Conjugation kits
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab212723の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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特記事項 |
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IHC-P
Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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機能
Involved in osteopontin/bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias. -
配列類似性
Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family. -
細胞内局在
Lysosome. - Information by UniProt
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参照データベース
- Entrez Gene: 54 Human
- Omim: 171640 Human
- SwissProt: P13686 Human
- Unigene: 1211 Human
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別名
- Type 5 acid phosphatase antibody
- Acid phosphatase 5 tartrate resistant antibody
- Acid phosphatase 5, tartrate resistant antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (4)
ab212723 は 4 報の論文で使用されています。
- Wheelis SE et al. Cellular and Molecular Dynamics during Early Oral Osseointegration: A Comprehensive Characterization in the Lewis Rat. ACS Biomater Sci Eng 7:2392-2407 (2021). PubMed: 33625829
- Peng Y et al. Glucocorticoids Disrupt Skeletal Angiogenesis Through Transrepression of NF-?B-Mediated Preosteoclast Pdgfb Transcription in Young Mice. J Bone Miner Res 35:1188-1202 (2020). PubMed: 32078184
- Dai J et al. Osteoclast-derived exosomal let-7a-5p targets Smad2 to promote the hypertrophic differentiation of chondrocytes. Am J Physiol Cell Physiol N/A:N/A (2020). PubMed: 32374679
- Gao B et al. Macrophage-lineage TRAP+ cells recruit periosteum-derived cells for periosteal osteogenesis and regeneration. J Clin Invest 129:2578-2594 (2019). PubMed: 30946695