PHAF1
Function
Plays a regulatory role in autophagic activity. In complex with BCAS3, associates with the autophagosome formation site during both non-selective and selective autophagy.
Sequence Similarities
Belongs to the PHAF1 family.
Cellular localization
- Cytoplasm
- Preautophagosomal structure
- The BCAS3:PHAF1 complex is recruited to the preautophagosomal structures adjacent to the damaged mitochondria upon mitophagy in a PRKN-PINK1 dependent manner.
Alternative names
C16orf6, C16orf70, PHAF1, Phagosome assembly factor 1