PCOLCE2
Function
Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1.
Post-translational modifications
O-glycosylated; contains sialic acid.
Tissue Specificity
Highly expressed in the heart, trabecular meshwork, pituitary gland, bladder, mammary gland, trachea and placenta and weakly expressed in the brain. Expressed in cartilage.
Cellular localization
- Secreted
Alternative names
PCPE2, UNQ250/PRO287, PCOLCE2, Procollagen C-endopeptidase enhancer 2, Procollagen COOH-terminal proteinase enhancer 2, PCPE-2, Procollagen C-proteinase enhancer 2