Gas1
Function
Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells. Binds 20(S)-hydroxycholesterol (20(S)-OHC) (PubMed:34799735).
Cellular localization
- Cell membrane
- Lipid-anchor
- GPI-anchor
Alternative names
Gas-1, Gas1, Growth arrest-specific protein 1, GAS-1