Fcgr3

Function

Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor which binds to IgG1, IgG2a and IgG2b (PubMed:17558411). Mediates neutrophil activation by IgG complexes redundantly with Fcgr4 (PubMed:18097064).

Cellular localization

• Cell membrane
• Single-pass type I membrane protein

Alternative names

CD16, Low affinity immunoglobulin gamma Fc region receptor III, IgG Fc receptor III, Fc-gamma RIII, FcRIII, Fcgr3

Database links

swissprot:P08508 swissprot:P08101 swissprot:Q5D5I8 swissprot:Q5D5J5 swissprot:Q7TMW9 swissprot:Q9ES92 entrezGene:14130 entrezGene:14131

Other research areas

• Immunology & Infectious Disease