Anti-T Cell Receptor 抗体 [JOVI.1] (ab5465)
Key features and details
- Mouse monoclonal [JOVI.1] to T Cell Receptor
- Suitable for: IHC-Fr, IP, Flow Cyt
- Reacts with: Human
- Isotype: IgG2a
製品の概要
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製品名
Anti-T Cell Receptor antibody [JOVI.1] -
製品の詳細
Mouse monoclonal [JOVI.1] to T Cell Receptor -
由来種
Mouse -
特異性
Specific to the C beta 1 chain -
アプリケーション
適用あり: IHC-Fr, IP, Flow Cytmore details -
種交差性
交差種: Human -
免疫原
Thymus, spleen and mesenteric lymph nodes isolated from a mouse transgenic for human Vb3 TcR.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Constituent: PBS -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
JOVI.1 -
ミエローマ
NS1 -
アイソタイプ
IgG2a -
研究分野
関連製品
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Compatible Secondaries
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Conjugation kits
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Isotype control
アプリケーション
Our Abpromise guarantee covers the use of ab5465 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-Fr | Use at an assay dependent concentration. | |
| IP | Use at an assay dependent concentration. | |
| Flow Cyt | Use at an assay dependent concentration. ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
|
ターゲット情報
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関連性
Two distinct types of T-cell antigen receptors have been identified: the alpha/beta heterodimer found on functional helper and cytotoxic T cells, and the gamma/delta heterodimer. The latter is first detected approximately 2 days before the appearance of cell-surface alpha/beta heterodimer during T-cell ontogeny. -
細胞内局在
Cell Membrane -
参照データベース
- Entrez Gene: 6964 Human
- Entrez Gene: 6965 Human
- Omim: 186810 Human
- Omim: 186970 Human
- SwissProt: P04234 Human
- SwissProt: P09693 Human
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別名
- CD3g antigen antibody
- CD3 antigen delta subunit antibody
- CD3 DELTA antibody
see all
プロトコール
参考文献 (2)
ab5465 は 2 報の論文で使用されています。
- Chen IJ et al. Lateral compartmentalization of T cell receptor versus CD45 by galectin-N-glycan binding and microfilaments coordinate basal and activation signaling. J Biol Chem 282:35361-72 (2007). PubMed: 17897956
- Viney JL et al. Generation of monoclonal antibodies against a human T cell receptor beta chain expressed in transgenic mice. Hybridoma 11:701-13 (1992). PubMed: 1284120
