Anti-Synapsin I (phospho S603) 抗体 (ab13879)

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製品の概要

  • 製品名
    Anti-Synapsin I (phospho S603) antibody
    Synapsin I 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Synapsin I (phospho S603)
  • 由来種
    Rabbit
  • 特異性
    The antibody is specific for Synapsin I phosphorylated at Ser603.
  • アプリケーション
    適用あり: Dot blot, WBmore details
  • 種交差性
    交差種: Rat
  • 免疫原

    This antibody was developed against synthetic phosphopeptide corresponding to amino acids residues surrounding the phospho-Ser603 of rat Synapsin I.

  • 特記事項
    Aliquots may be taken without freeze/thawing due to the presence of 50% glycerol.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    pH: 7.50
    Constituents: 0.238% HEPES, 0.87% Sodium chloride, 0.01% BSA
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項（精製）
    The antibody was purified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab13879 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Dot blot 1/1000.
WB 1/1000. Predicted molecular weight: 84.6 kDa.

ターゲット情報

  • 機能
    Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.
  • 関連疾患
    Defects in SYN1 are a cause of epilepsy X-linked with variable learning disabilities and behavior disorders [MIM:300491]. XELBD is characterized by variable combinations of epilepsy, learning difficulties, macrocephaly, and aggressive behavior.
  • 配列類似性
    Belongs to the synapsin family.
  • 翻訳後修飾
    Substrate of at least four different protein kinases. It is probable that phosphorylation plays a role in the regulation of synapsin-1 in the nerve terminal. Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在
    Cell junction > synapse. Golgi apparatus.
  • Information by UniProt
  • 参照データベース
    • 別名
      • Brain protein 4.1 antibody
      • SYN 1 antibody
      • SYN 1a antibody
      • SYN 1b antibody
      • SYN I antibody
      • SYN1 antibody
      • SYN1_HUMAN antibody
      • SYN1a antibody
      • SYN1b antibody
      • Synapsin 1 antibody
      • Synapsin I antibody
      • Synapsin-1 antibody
      • Synapsin1 antibody
      • SynapsinI antibody
      • SYNI antibody
      see all

    画像

    • Western blot - Anti-Synapsin I (phospho S603) antibody (ab13879)
      Western blot - Anti-Synapsin I (phospho S603) antibody (ab13879)
      Right lane-ab13879 at 1/1000 dilution detecting synapsin I by Western blot. Left lane-Peptide block. Right lane-ab13879 at 1/1000 dilution detecting synapsin I by Western blot. Left lane-Peptide block.

    プロトコール

    参考文献

    ab13879 has not yet been referenced specifically in any publications.

    ab13879 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    レビューと Q&A

    レビューを送る 質問を送る

    1 Review or Q&A

    10
    Votes: Highest First

    Is this product's immunogen S609 or S603?

    Thank you for your enquiry. I can confirm that the immunogen for this product is phospho-Ser603 of rat Synapsin I. I sincerely apologize that we had a typing error on the datasheet and rest assured that it has now been corrected. Thank you agai...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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