Anti-Swd2 抗体 (ab220240)
Key features and details
- Rabbit polyclonal to Swd2
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
製品の概要
-
製品名
Anti-Swd2 antibody -
製品の詳細
Rabbit polyclonal to Swd2 -
由来種
Rabbit -
アプリケーション
適用あり: WB, ICC/IFmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Chicken, Xenopus laevis, Zebrafish, Xenopus tropicalis
-
免疫原
Recombinant fragment corresponding to Human Swd2 aa 200 to the C-terminus.
Database link: Q6UXN9 -
ポジティブ･コントロール
- U-251 MG cell lysate; U-251 MG cells.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 59% PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab220240の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 0.04 - 0.4 µg/ml. Predicted molecular weight: 35 kDa.
|
|
| ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
|
| 特記事項 |
|---|
|
WB
Use a concentration of 0.04 - 0.4 µg/ml. Predicted molecular weight: 35 kDa. |
|
ICC/IF
Use a concentration of 0.25 - 2 µg/ml. |
ターゲット情報
-
機能
Regulatory component of the SET1 complex implicated in the tethering of this complex to transcriptional start sites of active genes. Facilitates histone H3 'Lys-4' methylation via recruitment of the SETD1A or SETD1B to the 'Ser-5' phosphorylated C-terminal domain (CTD) of RNA polymerase II large subunit (POLR2A). Component of PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. -
配列類似性
Belongs to the WD repeat SWD2 family.
Contains 6 WD repeats. -
細胞内局在
Nucleus. Associates with chromatin. - Information by UniProt
-
参照データベース
- Entrez Gene: 415942 Chicken
- Entrez Gene: 80335 Human
- Entrez Gene: 77305 Mouse
- Entrez Gene: 494657 Xenopus laevis
- Entrez Gene: 735072 Xenopus laevis
- Entrez Gene: 48141 Xenopus tropicalis
- Entrez Gene: 321614 Zebrafish
- Omim: 611059 Human
see all -
別名
- TMEM113 antibody
- MST107 antibody
- MSTP107 antibody
see all
画像
-
Immunocytochemistry/ Immunofluorescence - Anti-Swd2 antibody (ab220240)
Immunofluorescent analysis of U-251 MG cells (PFA-fixed/Triton X-100 permeabilized) labeling Swd2 with ab220240 at 4μg/ml (green).
-
Western blot - Anti-Swd2 antibody (ab220240)All lanes : Anti-Swd2 antibody (ab220240) at 1/100 dilution
Lane 1 : RT-4 cell lysate
Lane 2 : U-251 MG cell lysate
Predicted band size: 35 kDa
プロトコール
データシートおよび資料
-
Datasheet download
参考文献 (1)
ab220240 は 1 報の論文で使用されています。
- Duan Z et al. TMT-based quantitative proteomics analysis reveals the attenuated replication mechanism of Newcastle disease virus caused by nuclear localization signal mutation in viral matrix protein. Virulence 11:607-635 (2020). PubMed: 32420802
