Anti-Sumo 3 抗体 (ab5317)
Key features and details
- Rabbit polyclonal to Sumo 3
- Suitable for: WB
- Reacts with: Arabidopsis thaliana
- Isotype: IgG
製品の概要
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製品名
Anti-Sumo 3 antibody
Sumo 3 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Sumo 3 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Arabidopsis thaliana -
免疫原
Recombinant full length protein (Arabidopsis thaliana).
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Concentration information loading... -
精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab5317の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | (1) |
1/1000. Predicted molecular weight: 12 kDa.
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| 特記事項 |
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WB
1/1000. Predicted molecular weight: 12 kDa. |
ターゲット情報
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機能
Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. -
組織特異性
Expressed predominantly in liver. -
配列類似性
Belongs to the ubiquitin family. SUMO subfamily.
Contains 1 ubiquitin-like domain. -
翻訳後修飾
Polymeric chains can be formed through Lys-11 cross-linking.
Cleavage of precursor form by SENP1, SENP2 or SENP5 is necessary for function. -
細胞内局在
Cytoplasm. - Information by UniProt
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別名
- Small ubiquitin like modifier 3 antibody
- Small ubiquitin related modifier 3 antibody
- Small ubiquitin-related modifier 3 antibody
see all
画像
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Western blot - Anti-Sumo 3 antibody (ab5317)
Western blots of SUMO1 and SUMO3 antibody on arabidopsis extracts heat treated for the indicated times by moving them from 24 to 37 degrees C. The panel on the left was using ab5316, the panel on the right was using ab5317 - both antibodies were used at a dilution of 1/1000.
Western blots of SUMO1 and SUMO3 antibody on arabidopsis extracts heat treated for the indicated times by moving them from 24 to 37 degrees C. The panel on the left was using ab5316, the panel on the right was using ab5317 - both antibodies were used at a dilution of 1/1000.
データシートおよび資料
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Datasheet download
参考文献 (3)
ab5317 は 3 報の論文で使用されています。
- Cheng X et al. Sumoylation of Turnip mosaic virus RNA Polymerase Promotes Viral Infection by Counteracting the Host NPR1-Mediated Immune Response. Plant Cell 29:508-525 (2017). PubMed: 28223439
- Budhiraja R et al. Substrates related to chromatin and to RNA-dependent processes are modified by Arabidopsis SUMO isoforms that differ in a conserved residue with influence on desumoylation. Plant Physiol 149:1529-40 (2009). WB ; Arabidopsis thaliana . PubMed: 19151129
- Kurepa J et al. The small ubiquitin-like modifier (SUMO) protein modification system in Arabidopsis. Accumulation of SUMO1 and -2 conjugates is increased by stress. J Biol Chem 278:6862-72 (2003). PubMed: 12482876
