SU 5416 (Semaxanib), VEGFR-2 inhibitor (ab145056)
Key features and details
- Selective VEGFR-2 inhibitor
- CAS Number: 204005-46-9
- Purity: > 99%
- Soluble in ethanol to 10 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
SU 5416 (Semaxanib), VEGFR-2 inhibitor -
製品の詳細
Selective VEGFR-2 inhibitor -
別名
- Semaxinib
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精製度
> 99% -
CAS 番号
204005-46-9 -
構造式
製品の特性
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体系名
(3Z)-3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one -
分子量
238.28 -
分子式
C15H14N2O -
PubChem 登録番号
5329098 -
保存方法
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in ethanol to 10 mM and in DMSO to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CC1=CC(=C(N1)C=C2C3=CC=CC=C3NC2=O)C -
由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (3)
ab145056 は 3 報の論文で使用されています。
- Fan XX et al. Honokiol improves depression-like behaviors in rats by HIF-1α- VEGF signaling pathway activation. Front Pharmacol 13:968124 (2022). PubMed: 36091747
- Chang SH et al. Excessive mechanical loading promotes osteoarthritis through the gremlin-1-NF-?B pathway. Nat Commun 10:1442 (2019). PubMed: 30926814
- Tanaka H et al. Therapeutic impact of dietary vitamin D supplementation for preventing right ventricular remodeling and improving survival in pulmonary hypertension. PLoS One 12:e0180615 (2017). Rat . PubMed: 28686688