Anti-Streptolysin 抗体 [6D11] (ab23501)
Key features and details
- Mouse monoclonal [6D11] to Streptolysin
- Suitable for: ELISA
- Reacts with: Streptococcus
- Isotype: IgG1
製品の概要
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製品名
Anti-Streptolysin antibody [6D11] -
製品の詳細
Mouse monoclonal [6D11] to Streptolysin -
由来種
Mouse -
特異性
ab23501 is specific for oxidized streptolysin but cross reacts with untreated streptolysin -
アプリケーション
適用あり: ELISAmore details -
種交差性
交差種: Streptococcus -
免疫原
Cysteine chloride oxidized streptolysin.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.40
Preservative: 0.097% Sodium azide
Constituents: 0.0268% PBS, 2.9% Sodium chloride -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
6D11 -
ミエローマ
x63-Ag8.653 -
アイソタイプ
IgG1 -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab23501の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ELISA |
1/400.
|
特記事項 |
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ELISA
1/400. |
ターゲット情報
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関連性
Bacteria of the Streptococcus genera produce the exotoxin streptolysin. Anti-streptolysin antibody titers in patients are measured as a marker of inflammation. Streptolysin is also an important tool in cell biology due to its hemolytic activity and the ability to permeabilize plasma membranes. Sulfhydryl-activated toxin. Is able to lyse cholesterol containing membranes. Can be reversibly inactivated by oxidation. Cholesterol is the receptor for the binding of these toxins to eukaryotic cell membranes. -
細胞内局在
Secreted -
別名
- Slo antibody
- Streptolysin O antibody
- Thiol activated cytolysin antibody
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab23501 は 4 報の論文で使用されています。
- Lin CY et al. Autophagy Receptor Tollip Facilitates Bacterial Autophagy by Recruiting Galectin-7 in Response to Group A Streptococcus Infection. Front Cell Infect Microbiol 10:583137 (2020). PubMed: 33425778
- Horiuchi T et al. Floating chip mounting system driven by repulsive force of permanent magnets for multiple on-site SPR immunoassay measurements. Sensors (Basel) 12:13964-84 (2012). PubMed: 23202030
- Horiuchi T et al. Passive fluidic chip composed of integrated vertical capillary tubes developed for on-site SPR immunoassay analysis targeting real samples. Sensors (Basel) 12:7095-108 (2012). PubMed: 22969339
- Keyel PA et al. Streptolysin O clearance through sequestration into blebs that bud passively from the plasma membrane. J Cell Sci 124:2414-23 (2011). ICC/IF, WB . PubMed: 21693578