Anti-Stanniocalcin 1/STC 抗体 [EPR6055] (ab124891)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR6055] to Stanniocalcin 1/STC
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
製品の概要
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製品名
Anti-Stanniocalcin 1/STC antibody [EPR6055]
Stanniocalcin 1/STC 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR6055] to Stanniocalcin 1/STC -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details
適用なし: ICC/IF or IHC-P -
種交差性
交差種: Human
非交差種: Mouse, Rat -
免疫原
Synthetic peptide within Human Stanniocalcin 1/STC aa 200-300 (C terminal). The exact sequence is proprietary.
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ポジティブ・コントロール
- Human Prostate, Ovary cancer and Plasma lysates.
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
解離定数(KD 値)
KD = 2.10 x 10 -12 M Learn more about KD -
バッファー
pH: 7.2
Preservative: 0.05% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
EPR6055 -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab124891の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/1000 - 1/10000. Detects a band of approximately 31-35 kDa (predicted molecular weight: 28 kDa).
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特記事項 |
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WB
1/1000 - 1/10000. Detects a band of approximately 31-35 kDa (predicted molecular weight: 28 kDa). |
ターゲット情報
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機能
Stimulates renal phosphate reabsorption, and could therefore prevent hypercalcemia. -
組織特異性
Expressed in most tissues, with the highest levels in ovary, prostate, heart, kidney and thyroid. In the kidney, expression is confined to the nephron, specifically in the distal convoluted tubule and in the collecting tubule. Not detected in the brain, liver, spleen, peripheral blood leukocytes and adrenal medulla. -
配列類似性
Belongs to the stanniocalcin family. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 6781 Human
- Omim: 601185 Human
- SwissProt: P52823 Human
- Unigene: 25590 Human
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別名
- Stanniocalcin 1 antibody
- Stanniocalcin antibody
- Stanniocalcin-1 antibody
see all
画像
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All lanes : Anti-Stanniocalcin 1/STC antibody [EPR6055] (ab124891) at 1/1000 dilution
Lane 1 : Human Prostate lysate
Lane 2 : Human Ovary cancer lysate
Lane 3 : Human Plasma lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat anti-Rabbit HRP at 1/2000 dilution
Predicted band size: 28 kDa
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab124891 は 2 報の論文で使用されています。
- Zhang C et al. Targeting POLE2 Creates a Novel Vulnerability in Renal Cell Carcinoma via Modulating Stanniocalcin 1. Front Cell Dev Biol 9:622344 (2021). PubMed: 33644060
- Mou Z et al. Transcriptomic Analysis of Glycolysis-Related Genes Reveals an Independent Signature of Bladder Carcinoma. Front Genet 11:566918 (2020). PubMed: 33424916