ab16030 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

ab16030 は 74 報の論文で使用されています。

  • Miyawaki A  et al. IL-11 prevents IFN-?-induced hepatocyte death through selective downregulation of IFN-?/STAT1 signaling and ROS scavenging. PLoS One 14:e0211123 (2019). PubMed: 30779746
  • Zhou B  et al. Protective Role of SOCS3 Modified Bone Marrow Mesenchymal Stem Cells in Hypoxia-Induced Injury of PC12 Cells. J Mol Neurosci 67:400-410 (2019). PubMed: 30648230
  • Chen Y  et al. MicroRNA-19a-3p promotes rheumatoid arthritis fibroblast-like synoviocytes via targeting SOCS3. J Cell Biochem N/A:N/A (2019). PubMed: 30854695
  • Wang XY  et al. MiR-128-3p accelerates cardiovascular calcification and insulin resistance through ISL1-dependent Wnt pathway in type 2 diabetes mellitus rats. J Cell Physiol 234:4997-5010 (2019). PubMed: 30341898
  • Achanta S  et al. Single-Cell Gene Expression Analysis Identifies Chronic Alcohol-Mediated Shift in Hepatocyte Molecular States After Partial Hepatectomy. Gene Expr 19:97-119 (2019). PubMed: 30189915
  • Gao F  et al. Therapeutic role of miR-19a/19b in cardiac regeneration and protection from myocardial infarction. Nat Commun 10:1802 (2019). PubMed: 30996254
  • Del Gaudio N  et al. BRD9 binds cell type-specific chromatin regions regulating leukemic cell survival via STAT5 inhibition. Cell Death Dis 10:338 (2019). PubMed: 31000698
  • Yu HR  et al. Resveratrol Treatment Ameliorates Leptin Resistance and Adiposity Programed by the Combined Effect of Maternal and Post-Weaning High-Fat Diet. Mol Nutr Food Res N/A:e1801385 (2019). PubMed: 31004461
  • Jiang L  et al. The Pros1/Tyro3 axis protects against periodontitis by modulating STAT/SOCS signalling. J Cell Mol Med 23:2769-2781 (2019). PubMed: 30729671
  • Tsai CC  et al. Melatonin alleviates liver steatosis induced by prenatal dexamethasone exposure and postnatal high-fat diet. Exp Ther Med 16:917-924 (2018). PubMed: 30112044
  • Morin-Brureau M  et al. Microglial phenotypes in the human epileptic temporal lobe. Brain 141:3343-3360 (2018). PubMed: 30462183
  • Wilson HM  et al. Characterization of the Myocardial Inflammatory Response in Acute Stress-Induced (Takotsubo) Cardiomyopathy. JACC Basic Transl Sci 3:766-778 (2018). PubMed: 30623136
  • Li M  et al. Icariin Ameliorates Palmitate-Induced Insulin Resistance Through Reducing Thioredoxin-Interacting Protein (TXNIP) and Suppressing ER Stress in C2C12 Myotubes. Front Pharmacol 9:1180 (2018). PubMed: 30459603
  • Abe T  et al. Clinicopathological Significance and Antitumor Effect of MPHOSPH1 in Testicular Germ Cell Tumor. J Cancer 9:4440-4448 (2018). PubMed: 30519350
  • Gallaher ZR & Steward O Modest enhancement of sensory axon regeneration in the sciatic nerve with conditional co-deletion of PTEN and SOCS3 in the dorsal root ganglia of adult mice. Exp Neurol 303:120-133 (2018). WB . PubMed: 29458059
  • Zheng XB  et al. miR-203 inhibits augmented proliferation and metastasis of hepatocellular carcinoma residual in the promoted regenerating liver. Cancer Sci 108:338-346 (2017). PubMed: 28100026
  • Roselló-Díez A  et al. Altered paracrine signaling from the injured knee joint impairs postnatal long bone growth. Elife 6:N/A (2017). PubMed: 28741471
  • Yu L  et al. SOCS3 overexpression inhibits advanced glycation end product-induced EMT in proximal tubule epithelial cells. Exp Ther Med 13:3109-3115 (2017). PubMed: 28587386
  • Sobotta S  et al. Model Based Targeting of IL-6-Induced Inflammatory Responses in Cultured Primary Hepatocytes to Improve Application of the JAK Inhibitor Ruxolitinib. Front Physiol 8:775 (2017). PubMed: 29062282
  • Rahman TU  et al. Hypertriglyceridemia in female rats during pregnancy induces obesity in male offspring via altering hypothalamic leptin signaling. Oncotarget 8:53450-53464 (2017). PubMed: 28881823
  • DePaul MA  et al. Combinatory repair strategy to promote axon regeneration and functional recovery after chronic spinal cord injury. Sci Rep 7:9018 (2017). IHC ; Rat . PubMed: 28827771
  • Wang H  et al. HuoXueJieDu Formula Alleviates Diabetic Retinopathy in Rats by Inhibiting SOCS3-STAT3 and TIMP1-A2M Pathways. Int J Genomics 2017:4832125 (2017). PubMed: 29318137
  • Shaw EJ  et al. Intestinal epithelial suppressor of cytokine signaling 3 (SOCS3) impacts on mucosal homeostasis in a model of chronic inflammation. Immun Inflamm Dis 5:336-345 (2017). ICC/IF ; Mouse . PubMed: 28508554
  • Hwang M  et al. Epac2a-null mice exhibit obesity-prone nature more susceptible to leptin resistance. Int J Obes (Lond) 41:279-288 (2017). WB ; Mouse . PubMed: 27867203
  • Lv R  et al. IL-33 Attenuates Sepsis by Inhibiting IL-17 Receptor Signaling through Upregulation of SOCS3. Cell Physiol Biochem 42:1961-1972 (2017). PubMed: 28793286
  • Galoian K  et al. Effect of cytostatic proline rich polypeptide-1 on tumor suppressors of inflammation pathway signaling in chondrosarcoma. Mol Clin Oncol 5:618-624 (2016). WB ; Human . PubMed: 27900099
  • Chuang Y  et al. Regulation of the IL-10-driven macrophage phenotype under incoherent stimuli. Innate Immun 22:647-657 (2016). WB ; Mouse . PubMed: 27670945
  • Roncero AM  et al. Contribution of JAK2 mutations to T-cell lymphoblastic lymphoma development. Leukemia 30:94-103 (2016). WB ; Human . PubMed: 26216197
  • Huang YH  et al. Postnatal High-Fat Diet Increases Liver Steatosis and Apoptosis Threatened by Prenatal Dexamethasone through the Oxidative Effect. Int J Mol Sci 17:369 (2016). WB ; Rat . PubMed: 26978357
  • Kim MS  et al. Dysregulated JAK2 expression by TrkC promotes metastasis potential, and EMT program of metastatic breast cancer. Sci Rep 6:33899 (2016). WB . PubMed: 27654855
  • Wang Y  et al. Up-regulation of miR-203 expression induces endothelial inflammatory response: Potential role in preeclampsia. Am J Reprod Immunol 76:482-490 (2016). PubMed: 27753461
  • Hoffmann J  et al. Viral and bacterial co-infection in severe pneumonia triggers innate immune responses and specifically enhances IP-10: a translational study. Sci Rep 6:38532 (2016). PubMed: 27922126
  • Singh P  et al. Differential effects of leptin on adiponectin expression with weight gain versus obesity. Int J Obes (Lond) 40:266-74 (2016). PubMed: 26374448
  • Hackett AR  et al. STAT3 and SOCS3 regulate NG2 cell proliferation and differentiation after contusive spinal cord injury. Neurobiol Dis 89:10-22 (2016). PubMed: 26804026
  • Wörmann SM  et al. Loss of P53 Function Activates JAK2-STAT3 Signaling to Promote Pancreatic Tumor Growth, Stroma Modification, and Gemcitabine Resistance in Mice and Is Associated With Patient Survival. Gastroenterology 151:180-193.e12 (2016). PubMed: 27003603
  • Chen WB  et al. Conditional ablation of HDAC3 in islet beta cells results in glucose intolerance and enhanced susceptibility to STZ-induced diabetes. Oncotarget 7:57485-57497 (2016). PubMed: 27542279
  • Yoo JY  et al. Protein Inhibitor of Activated STAT3 (PIAS3) Is Down-Regulated in Eutopic Endometrium of Women with Endometriosis. Biol Reprod 95:11 (2016). PubMed: 27226311
  • Zhang X  et al. Reactive oxygen species-induced TXNIP drives fructose-mediated hepatic inflammation and lipid accumulation through NLRP3 inflammasome activation. Antioxid Redox Signal 22:848-70 (2015). PubMed: 25602171
  • Guo F  et al. FXR induces SOCS3 and suppresses hepatocellular carcinoma. Oncotarget 6:34606-16 (2015). WB ; Human . PubMed: 26416445
  • Kim MH  et al. Suppressor of cytokine signaling (SOCS) genes are silenced by DNA hypermethylation and histone deacetylation and regulate response to radiotherapy in cervical cancer cells. PLoS One 10:e0123133 (2015). IHC ; Human . PubMed: 25849377
  • Trilling M  et al. "Activated" STAT proteins: a paradoxical consequence of inhibited JAK-STAT signaling in cytomegalovirus-infected cells. J Immunol 192:447-58 (2014). Mouse . PubMed: 24319264
  • Webster KE  et al. IL-17-producing NKT cells depend exclusively on IL-7 for homeostasis and survival. Mucosal Immunol N/A:N/A (2014). Human . PubMed: 24448098
  • Krow-Lucal ER  et al. Distinct functional programming of human fetal and adult monocytes. Blood 123:1897-904 (2014). Flow Cyt ; Human . PubMed: 24518760
  • Kneitz B  et al. Survival in patients with high-risk prostate cancer is predicted by miR-221, which regulates proliferation, apoptosis, and invasion of prostate cancer cells by inhibiting IRF2 and SOCS3. Cancer Res 74:2591-603 (2014). PubMed: 24607843
  • Nguyen T  et al. The effects of resting and exercise serum from children with cystic fibrosis on C2C12 myoblast proliferation in vitro. Physiol Rep 2:N/A (2014). WB ; Human . PubMed: 24944290
  • de Laat MA  et al. Hyperinsulinemia Down-Regulates TLR4 Expression in the Mammalian Heart. Front Endocrinol (Lausanne) 5:120 (2014). WB ; Rat . PubMed: 25101057
  • Collins AS  et al. Hepatitis C virus (HCV)-induced suppressor of cytokine signaling (SOCS) 3 regulates proinflammatory TNF-a responses. J Leukoc Biol 96:255-63 (2014). PubMed: 24659790
  • Yonamine CY  et al. Beta hydroxy beta methylbutyrate supplementation impairs peripheral insulin sensitivity in healthy sedentary Wistar rats. Acta Physiol (Oxf) 212:62-74 (2014). PubMed: 24962220
  • Williams KW  et al. Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis. Cell Metab 20:471-82 (2014). PubMed: 25017942
  • Schmidt-Edelkraut U  et al. Zac1 regulates astroglial differentiation of neural stem cells through Socs3. Stem Cells 31:1621-32 (2013). PubMed: 23630160
  • Zhao Y  et al. The coregulator, repressor of estrogen receptor activity (REA), is a crucial regulator of the timing and magnitude of uterine decidualization. Endocrinology 154:1349-60 (2013). PubMed: 23392257
  • Khalaf H  et al. Suppression of inflammatory gene expression in T cells by Porphyromonas gingivalis is mediated by targeting MAPK signaling. Cell Mol Immunol 10:413-22 (2013). WB . PubMed: 23892429
  • Collins AS  et al. miR-19a: an effective regulator of SOCS3 and enhancer of JAK-STAT signalling. PLoS One 8:e69090 (2013). IHC ; Mouse . PubMed: 23894411
  • McKay BR  et al. Elevated SOCS3 and altered IL-6 signaling is associated with age-related human muscle stem cell dysfunction. Am J Physiol Cell Physiol 304:C717-28 (2013). PubMed: 23392112
  • Alcazar MA  et al. Early postnatal hyperalimentation impairs renal function via SOCS-3 mediated renal postreceptor leptin resistance. Endocrinology 153:1397-410 (2012). PubMed: 22253420
  • Zeitvogel J  et al. Human Primary Keratinocytes Show Restricted Ability to Up-regulate Suppressor of Cytokine Signaling (SOCS)3 Protein Compared with Autologous Macrophages. J Biol Chem 287:9923-30 (2012). Flow Cyt ; Human . PubMed: 22294695
  • Li Y  et al. STAT1, STAT6 and adenosine 3',5'-cyclic monophosphate (cAMP) signaling drive SOCS3 expression in inactive ulcerative colitis. Mol Med 18:1412-9 (2012). PubMed: 23154639
  • Gupta GK  et al. Vitamin D deficiency induces cardiac hypertrophy and inflammation in epicardial adipose tissue in hypercholesterolemic swine. Exp Mol Pathol 93:82-90 (2012). PubMed: 22537546
  • Li Y  et al. IL-6-induced DNMT1 activity mediates SOCS3 promoter hypermethylation in ulcerative colitis-related colorectal cancer. Carcinogenesis 33:1889-96 (2012). WB ; Human . PubMed: 22739025
  • Kern M  et al. Linagliptin improves insulin sensitivity and hepatic steatosis in diet-induced obesity. PLoS One 7:e38744 (2012). IHC . PubMed: 22761701
  • White GE  et al. Suppressor of cytokine signalling protein SOCS3 expression is increased at sites of acute and chronic inflammation. J Mol Histol 42:137-51 (2011). WB . PubMed: 21360047
  • Gupta GK  et al. Suppressor of cytokine signaling-3 and intimal hyperplasia in porcine coronary arteries following coronary intervention. Exp Mol Pathol 91:346-52 (2011). PubMed: 21540027
  • Scheller EL  et al. Zoledronic acid inhibits macrophage SOCS3 expression and enhances cytokine production. J Cell Biochem 112:3364-72 (2011). PubMed: 21751240
  • Wang Y  et al. Elevated maternal soluble Gp130 and IL-6 levels and reduced Gp130 and SOCS-3 expressions in women complicated with preeclampsia. Hypertension 57:336-42 (2011). PubMed: 21173340
  • Ghanim H  et al. A resveratrol and polyphenol preparation suppresses oxidative and inflammatory stress response to a high-fat, high-carbohydrate meal. J Clin Endocrinol Metab 96:1409-14 (2011). Human . PubMed: 21289251
  • Nguyen KD  et al. Serum amyloid A overrides Treg anergy via monocyte-dependent and Treg-intrinsic, SOCS3-associated pathways. Blood 117:3793-8 (2011). PubMed: 21325601
  • Ghanim H  et al. An antiinflammatory and reactive oxygen species suppressive effects of an extract of Polygonum cuspidatum containing resveratrol. J Clin Endocrinol Metab 95:E1-8 (2010). WB ; Human . PubMed: 20534755
  • Catania A  et al. The peptide NDP-MSH induces phenotype changes in the heart that resemble ischemic preconditioning. Peptides 31:116-22 (2010). WB ; Rat . PubMed: 19799952
  • Chen L  et al. Expressions of SOCS-1 and SOCS-3 in the myocardium of patients with sudden cardiac death. World J Emerg Med 1:99-103 (2010). PubMed: 25214949
  • Woolson HD  et al. Selective inhibition of cytokine-activated extracellular signal-regulated kinase by cyclic AMP via Epac1-dependent induction of suppressor of cytokine signalling-3. Cell Signal 21:1706-15 (2009). PubMed: 19632320
  • St John AL & Abraham SN Salmonella disrupts lymph node architecture by TLR4-mediated suppression of homeostatic chemokines. Nat Med 15:1259-65 (2009). IHC-Fr ; Mouse . PubMed: 19855398
  • Liu Y  et al. Unique expression of suppressor of cytokine signaling 3 is essential for classical macrophage activation in rodents in vitro and in vivo. J Immunol 180:6270-8 (2008). IHC-P ; Rat . PubMed: 18424750
  • Zhao S  et al. Altered interleukin-6 receptor, IL-6R and gp130, production and expression and decreased SOCS-3 expression in placentas from women with pre-eclampsia. Placenta 29:1024-8 (2008). IHC-P ; Human . PubMed: 18986700
  • Ma Z  et al. Mutations of HNF-1beta inhibit epithelial morphogenesis through dysregulation of SOCS-3. Proc Natl Acad Sci U S A 104:20386-91 (2007). PubMed: 18077349

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