Anti-SLFN14 抗体 (ab106406)
Key features and details
- Rabbit polyclonal to SLFN14
- Suitable for: ICC/IF, WB
- Reacts with: Mouse
- Isotype: IgG
製品の概要
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製品名
Anti-SLFN14 antibody
SLFN14 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to SLFN14 -
由来種
Rabbit -
特異性
At least two isoforms of SLFN14 are known to exist; ab106406 will recognize both isoforms. ab106406 is predicted not to crossreact with other SLFN proteins. -
アプリケーション
適用あり: ICC/IF, WBmore details -
種交差性
交差種: Mouse -
免疫原
A 16 amino acid synthetic peptide from near the C terminus of Human SLFN14 (NP_001123292).
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ポジティブ・コントロール
- Mouse kidney tissue lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab106406の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ICC/IF |
Use a concentration of 20 µg/ml.
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WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 104 kDa.
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特記事項 |
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ICC/IF
Use a concentration of 20 µg/ml. |
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 104 kDa. |
ターゲット情報
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配列類似性
Belongs to the Schlafen family. - Information by UniProt
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別名
- Schlafen 14 antibody
- Schlafen antibody
- Schlafen family member 14 antibody
see all
画像
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Immunofluorescence of SLFN14 in mouse kidney tissue with ab106406 at 20 ug/mL.
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Lane 1 : Anti-SLFN14 antibody (ab106406) at 1 µg/ml
Lane 2 : Anti-SLFN14 antibody (ab106406) at 2 µg/ml
All lanes : Mouse kidney tissue
lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 104 kDa
The lower band seen in the western blot may represent a post-translationally modified form of SLFN14.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (5)
ab106406 は 5 報の論文で使用されています。
- Fletcher SJ et al. Role of the novel endoribonuclease SLFN14 and its disease-causing mutations in ribosomal degradation. RNA 24:939-949 (2018). PubMed: 29678925
- Seong RK et al. Schlafen 14 (SLFN14) is a novel antiviral factor involved in the control of viral replication. Immunobiology 222:979-988 (2017). WB . PubMed: 28734654
- Marconi C et al. SLFN14-related thrombocytopenia: identification within a large series of patients with inherited thrombocytopenia. Thromb Haemost 115:1076-9 (2016). PubMed: 26769223
- Fletcher SJ et al. SLFN14 mutations underlie thrombocytopenia with excessive bleeding and platelet secretion defects. J Clin Invest 125:3600-5 (2015). PubMed: 26280575
- Pisareva VP et al. Characterization of Novel Ribosome-Associated Endoribonuclease SLFN14 from Rabbit Reticulocytes. Biochemistry 54:3286-301 (2015). PubMed: 25996083