製品の概要

  • 製品名

    SL 327, MEK inhibitor
  • 製品の詳細

    MEK inhibitor
  • 生理活性の詳細

    Centrally active, brain penetrant selective MEK1 and MEK2 inhibitor (IC50 values in in vitro assays are 0.18 and 0.22 μM, respectively).
  • 精製度

    > 99%
  • CAS 番号

    305350-87-2
  • 構造式

    Chemical Structure

製品の特性

参考文献

This product has been referenced in:

  • Wang X  et al. Significant neuroprotection against ischemic brain injury by inhibition of the MEK1 protein kinase in mice: exploration of potential mechanism associated with apoptosis. J Pharmacol Exp Ther 304:172-8 (2003). Read more (PubMed: 12490588) »
  • Scherle PA  et al. Regulation of cyclooxygenase-2 induction in the mouse uterus during decidualization. An event of early pregnancy. J Biol Chem 275:37086-92 (2000). Read more (PubMed: 10969080) »
  • Selcher JC  et al. A necessity for MAP kinase activation in mammalian spatial learning. Learn Mem 6:478-90 (0). Read more (PubMed: 10541468) »
See all 7 Publications for this product

レビューと Q&A

1-2 of 2 Abreviews or Q&A

Answer

Here are certificates of analysis for the product and lot numbers you have been assigned for your orders (PO numer xxxxx, orders xxxxx and xxxxxx).


If there are any problems please do let me know.

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Answer

Thank you for contacting us.


SL 327 (ab120082) and Kainic acid (ab120100) are both produced at >98% purity as determined by HPLC. I am checking which lots of these products have been assigned to you and then I will send the certificate of analysis for these lots.


The TTX is produced at >96% purity as determined by HPLC but we have stocks of this which is of >98% purity and I will again make sure that these stocks are being allocated to you and send the certificate of analysis.


In the meantime if you have any further questions please do not hesitate to ask.

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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