SKF 96365, TRP channel blocker (ab120280)

Submit a review Q&A (1)References (8)

製品の概要

  • 製品名
    SKF 96365, TRP channel blocker
  • 製品の詳細
    Blocker of TRP cation channels. Inhibits capacitative Ca2+ entry.
  • 生理活性の詳細
    Blocker of TRP cation channels. Inhibits capacitative Ca2+ entry.
  • 精製度
    > 99%

製品の特性

参考文献

This product has been referenced in:
  • Juvin V  et al. Pharmacological characterization and molecular determinants of the activation of transient receptor potential V2 channel orthologs by 2-aminoethoxydiphenyl borate. Mol Pharmacol 72:1258-68 (2007). Read more (PubMed: 17673572) »
  • Baba A  et al. Activity-evoked capacitative Ca2+ entry: implications in synaptic plasticity. J Neurosci 23:7737-41 (2003). Read more (PubMed: 12944501) »
  • Jan CR  et al. Multiple effects of 1-[beta-[3-(4-methoxyphenyl)propoxy]-4-methoxyphenethyl]-1H-imidazole hydrochloride (SKF 96365) on Ca2+ signaling in MDCK cells: depletion of thapsigargin-sensitive Ca2+ store followed by capacitative Ca2+ entry, activation of a direct Ca2+ entry, and inhibition of thapsigargin-induced capacitative Ca2+ entry. Naunyn Schmiedebergs Arch Pharmacol 359:92-101 (1999). Read more (PubMed: 10048593) »
See all 8 Publications for this product

ab120280 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

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Question

Dear ladies and gentlemen,



I have a technical question concerning the product SKF 96365 (product code: ab120280; former product code: Asc-280). Does this chemical consist of both stereoisomer or only one of them?



With best regards,

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Answer

Thanks for your email.



I can confirm that this is a racemic mixture of both stereoisomers.



If you need any further assistance in the future, please do not hesitate to contact me.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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