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Anti-Sin3b 抗体 (ab101843)

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Western blot - Anti-Sin3b antibody (ab101843)

    Key features and details

    • Rabbit polyclonal to Sin3b
    • Suitable for: WB
    • Reacts with: Human
    • Isotype: IgG

    製品の概要

    • 製品名

      Anti-Sin3b antibody
      Sin3b 一次抗体 製品一覧

    • 製品の詳細

      Rabbit polyclonal to Sin3b

    • 由来種

      Rabbit

    • アプリケーション

      適用あり: WBmore details

    • 種交差性

      交差種: Human
      交差が予測される動物種: Mouse, Rat

    • 免疫原

      Recombinant fragment, corresponding to a region within amino acids 15-215 of Human Sin3b.

    • ポジティブ･コントロール

      • HepG2 cell line and HCT116 whole cell lysate

    • 特記事項

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    製品の特性

    アプリケーション

    The Abpromise guarantee

    Abpromise保証は、 次のテスト済みアプリケーションにおけるab101843の使用に適用されます

    アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

    アプリケーション Abreviews 特記事項
    WB
    1/500 - 1/3000. Predicted molecular weight: 133 kDa.
    特記事項
    WB
    1/500 - 1/3000. Predicted molecular weight: 133 kDa.

    ターゲット情報

    • 機能

      Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.

    • 配列類似性

      Contains 3 PAH (paired amphipathic helix) domains.

    • 翻訳後修飾

      Ubiquitinated by RNF220 that leads to proteasomal degradation.

    • 細胞内局在

      Nucleus.
    • Information by UniProt

    • 参照データベース

      see all

    • 別名

      • Histone deacetylase complex subunit Sin3b antibody
      • Paired amphipathic helix protein Sin3b antibody
      • SIN3 homolog B transcription regulator antibody
      • SIN3 transcription regulator family member B antibody
      • SIN3 transcription regulator homolog B antibody
      • SIN3B antibody
      • SIN3B_HUMAN antibody
      • Transcriptional corepressor Sin3b antibody
      see all

    画像

    • Western blot - Anti-Sin3b antibody (ab101843)
      Western blot - Anti-Sin3b antibody (ab101843)
      Anti-Sin3b antibody (ab101843) at 1/1000 dilution + HCT116 whole cell lysate at 30 µg

      Predicted band size: 133 kDa



      10% SDS PAGE

    参考文献 (0)

    ab101843 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab101843 は論文での使用が確認できていません。

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