Anti-SHKBP1 抗体 (ab98148)
Key features and details
- Rabbit polyclonal to SHKBP1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-SHKBP1 antibody
SHKBP1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to SHKBP1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Cow
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免疫原
Recombinant protein fragment corresponding to a region within amino acids 162 and 447 of Human SHKBP1 (NP_612401).
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ポジティブ･コントロール
- A431 and H1299 cell lysates; PC13 xenograft
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab98148の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 76 kDa.
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| IHC-P |
1/100.
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| 特記事項 |
|---|
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WB
1/500 - 1/3000. Predicted molecular weight: 76 kDa. |
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IHC-P
1/100. |
ターゲット情報
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機能
Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation. -
配列類似性
Belongs to the KCTD3 family.
Contains 1 BTB (POZ) domain.
Contains 8 WD repeats. - Information by UniProt
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参照データベース
- Entrez Gene: 92799 Human
- Entrez Gene: 192192 Mouse
- SwissProt: Q8TBC3 Human
- SwissProt: Q6P7W2 Mouse
- Unigene: 26506 Human
- Unigene: 21297 Mouse
- Unigene: 470999 Mouse
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別名
- PP203 antibody
- Sb1 antibody
- SH3KBP1 binding protein 1 antibody
see all
画像
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Western blot - Anti-SHKBP1 antibody (ab98148)Anti-SHKBP1 antibody (ab98148) at 1/500 dilution + A431 whole cell lysate at 30 µg
Predicted band size: 76 kDa
7.5% SDS PAGE -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SHKBP1 antibody (ab98148)Immunohistochemical analysis of SHKBP1 in paraffin embedded PC13 xenograft, using ab98148 at a 1/100 dilution.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab98148 は論文での使用が確認できていません。