Anti-Serum Amyloid A 抗体 [115] (ab687)
製品の概要
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製品名
Anti-Serum Amyloid A antibody [115]
Serum Amyloid A 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [115] to Serum Amyloid A -
由来種
Mouse -
アプリケーション
適用あり: WB, Sandwich ELISAmore details -
種交差性
交差種: Human -
免疫原
Highly purified recombinant human serum amyloid A (MW: 12 kDa).
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特記事項
This product was changed from ascites to tissue culture supernatant on 6th March 2018. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
Constituent: PBS -
Concentration information loading...
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特記事項(精製)
Affinity purified from tissue culture supernatant. -
ポリ/モノ
モノクローナル -
クローン名
115 -
ミエローマ
unknown -
アイソタイプ
IgG1 -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
Our Abpromise guarantee covers the use of ab687 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
アプリケーション | Abreviews | 特記事項 |
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WB | Use at an assay dependent concentration. Use at an assay dependent dilution. This antibody, at a concentration of 0.1-0.5 µg/ml, will allow visualisation of 100 ng/lane of recombinant human SAA. | |
Sandwich ELISA | Use at an assay dependent concentration. |
ターゲット情報
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関連性
Function: Major acute phase reactant. Apolipoprotein of the HDL complex. Tissue specificity: Expressed by the liver; secreted in plasma. Disease: Note=Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function. Note=Elevated serum SAA protein levels may be associated with lung cancer. Similarity: Belongs to the SAA family. PTM: This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end. -
参照データベース
- Entrez Gene: 694827 Human
- Omim: 104750 Human
- SwissProt: P0DJI8 Human
- SwissProt: P0DJI9 Human
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別名
- Amyloid fibrils antibody
- SAA 2 antibody
- Serum amyloid A1 isoform 2 antibody
see all
画像
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All lanes : Anti-Serum Amyloid A antibody [115] (ab687) at 1/4000 dilution
Lanes 1-4 : Acute phase plasma samples
Lane 5 : Recombinant C-SAA
Lane 6 : Recombinant A-SAA
Lysates/proteins at 14 µg per lane.
Secondary
All lanes : Goat anti-mouse IgG-HRP at 1/10000 dilution
Developed using the ECL technique.
Exposure time: 5 seconds
データシートおよび資料
参考文献
This product has been referenced in:
- Heo SH et al. Comparative proteomic analysis in children with idiopathic short stature (ISS) before and after short-term recombinant human growth hormone (rhGH) therapy. Proteomics 13:1211-9 (2013). Human . Read more (PubMed: 23436750) »
- Jahangiri A et al. Serum amyloid A is found on ApoB-containing lipoproteins in obese humans with diabetes. Obesity (Silver Spring) 21:993-6 (2013). Read more (PubMed: 23784902) »