Anti-SEC61A 抗体 (ab1327)

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Western blot - Anti-SEC61A antibody (ab1327)

    Key features and details

    • Goat polyclonal to SEC61A
    • Suitable for: WB, IHC-P
    • Reacts with: Human
    • Isotype: IgG

    製品の概要

    • 製品名

      Anti-SEC61A antibody
      SEC61A 一次抗体 製品一覧

    • 製品の詳細

      Goat polyclonal to SEC61A

    • 由来種

      Goat

    • アプリケーション

      適用あり: WB, IHC-Pmore details

    • 種交差性

      交差種: Human
      交差が予測される動物種: Cow, Dog, Pig

    • 免疫原

      Synthetic peptide:

      C-KEQSEVGSMGALLF

      , corresponding to C terminal amino acids 463-476 of Human SEC61A(Peptide available as ab22804.)
      Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

    • 特記事項

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    製品の特性

    • 製品の状態

      Liquid

    • 保存方法

      Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    • バッファー

      pH: 7.30
      Preservative: 0.02% Sodium azide
      Constituents: 0.05% Tris, 0.5% BSA
    • Concentration information loading...

    • 精製度

      Immunogen affinity purified

    • 特記事項（精製）

      Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

    • ポリ/モノ

      ポリクローナル

    • アイソタイプ

      IgG

    • 研究分野

    アプリケーション

    The Abpromise guarantee

    Abpromise保証は、 次のテスト済みアプリケーションにおけるab1327の使用に適用されます

    アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

    アプリケーション Abreviews 特記事項
    WB
    Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 52 kDa).

    1 hour primary incubation is recommended for this product.
    IHC-P
    Use a concentration of 3.75 µg/ml.
    特記事項
    WB
    Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 52 kDa).

    1 hour primary incubation is recommended for this product.
    IHC-P
    Use a concentration of 3.75 µg/ml.

    ターゲット情報

    • 機能

      Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or through adapter proteins.

    • 配列類似性

      Belongs to the secY/SEC61-alpha family.

    • 細胞内局在

      Endoplasmic reticulum membrane.
    • Information by UniProt

    • 参照データベース

      • 別名

        • chunp6898 antibody
        • fb62c11 antibody
        • HSEC61 antibody
        • protein transport protein SEC61 alpha subunit antibody
        • protein transport protein Sec61 subunit alpha antibody
        • Protein transport protein Sec61 subunit alpha isoform 1 antibody
        • S61A1_HUMAN antibody
        • SEC 61 antibody
        • SEC 61A antibody
        • Sec61 alpha 1 antibody
        • Sec61 alpha 1 subunit antibody
        • Sec61 alpha 1 subunit (S. cerevisiae) antibody
        • Sec61 alpha-1 antibody
        • SEC61 antibody
        • Sec61 homolog antibody
        • SEC61A1 antibody
        • sec61aa antibody
        see all

      画像

      • Western blot - Anti-SEC61A antibody (ab1327)
        Western blot - Anti-SEC61A antibody (ab1327)
        Anti-SEC61A antibody (ab1327) at 1 µg/ml + Human cerebellum lysate in RIPA buffer at 35 µg

        Predicted band size: 52 kDa

      参考文献 (1)

      ab1327 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

      ab1327 は 1 報の論文で使用されています。

      • Lloyd DJ  et al. A point mutation in Sec61alpha1 leads to diabetes and hepatosteatosis in mice. Diabetes 59:460-70 (2010). ICC/IF ; Mouse . PubMed: 19934005

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