Anti-SDS3 抗体 (ab3740)
Key features and details
- Goat polyclonal to SDS3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-SDS3 antibody
SDS3 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to SDS3 -
由来種
Goat -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Rabbit, Chicken, Guinea pig, Cow, Dog, Turkey, Pig, Xenopus laevis, Chimpanzee, Zebrafish, Rhesus monkey, Gorilla, Orangutan, Xenopus tropicalis
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免疫原
Synthetic peptide (Human) - which represented a portion of human Suppressor of Defective Silencing 3 encoded in part by exons 7 and 8.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7
Preservative: 0.1% Sodium azide
Constituents: 0.021% PBS, 1.764% Sodium citrate, 1.815% Tris -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab3740の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/1000 - 1/5000. Predicted molecular weight: 45 kDa.
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| 特記事項 |
|---|
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WB
1/1000 - 1/5000. Predicted molecular weight: 45 kDa. |
ターゲット情報
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機能
Regulatory protein which represses transcription and augments histone deacetylase activity of HDAC1. May have a potential role in tumor suppressor pathways (By similarity). May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. -
組織特異性
Expressed in various cancer cell ines. -
配列類似性
Belongs to the SDS3 family. -
ドメイン
The C-terminus is involved in transcriptional repression by HDAC-independent mechanisms. - Information by UniProt
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参照データベース
- Entrez Gene: 64426 Human
- Entrez Gene: 445099 Zebrafish
- Omim: 608250 Human
- SwissProt: Q9H7L9 Human
- SwissProt: Q803C3 Zebrafish
- Unigene: 416630 Human
- Unigene: 602312 Human
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別名
- 2400003N08Rik antibody
- 2410008L21Rik antibody
- 45 kDa Sin3 associated polypeptide antibody
see all
画像
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Western blot - Anti-SDS3 antibody (ab3740)
Sample: HeLa whole cell lysate (50
µ g/lane)Antibody: Affinity purified Goat anti-SDS 3 (ab3740) used at the concentrations indicated.
Detection: ECL exposed for 2 minutes.
Sample: HeLa whole cell lysate (50
µg/lane) Antibody: Affinity purified Goat anti-SDS 3 (ab3740) used at the concentrations indicated.
Detection: ECL exposed for 2 minutes.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab3740 は 2 報の論文で使用されています。
- Ramakrishna S et al. Hyaluronan Binding Motifs of USP17 and SDS3 Exhibit Anti-Tumor Activity. PLoS One 7:e37772 (2012). WB ; Human . PubMed: 22662218
- Ramakrishna S et al. K63 specific deubiquitination of SDS3 by USP17 regulates HDAC activity. J Biol Chem : (2011). IP ; Human . PubMed: 21239494