Anti-SDS3 抗体 (ab3740)
Key features and details
- Goat polyclonal to SDS3
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
製品の概要
-
製品名
Anti-SDS3 antibody
SDS3 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to SDS3 -
由来種
Goat -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse, Human
交差が予測される動物種: Rabbit, Chicken, Guinea pig, Cow, Dog, Turkey, Pig, Xenopus laevis, Chimpanzee, Zebrafish, Rhesus monkey, Gorilla, Orangutan, Xenopus tropicalis
-
免疫原
Synthetic peptide (Human) - which represented a portion of human Suppressor of Defective Silencing 3 encoded in part by exons 7 and 8.
-
特記事項
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7
Preservative: 0.1% Sodium azide
Constituents: 0.021% PBS, 1.764% Sodium citrate, 1.815% Tris -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
Our Abpromise guarantee covers the use of ab3740 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | 1/1000 - 1/5000. Predicted molecular weight: 45 kDa. |
ターゲット情報
-
機能
Regulatory protein which represses transcription and augments histone deacetylase activity of HDAC1. May have a potential role in tumor suppressor pathways (By similarity). May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. -
組織特異性
Expressed in various cancer cell ines. -
配列類似性
Belongs to the SDS3 family. -
ドメイン
The C-terminus is involved in transcriptional repression by HDAC-independent mechanisms. - Information by UniProt
-
参照データベース
- Entrez Gene: 64426 Human
- Entrez Gene: 71954 Mouse
- Entrez Gene: 445099 Zebrafish
- Omim: 608250 Human
- SwissProt: Q9H7L9 Human
- SwissProt: Q8BR65 Mouse
- SwissProt: Q803C3 Zebrafish
- Unigene: 416630 Human
see all -
別名
- 2400003N08Rik antibody
- 2410008L21Rik antibody
- 45 kDa Sin3 associated polypeptide antibody
see all
画像
-
Western blot - Anti-SDS3 antibody (ab3740)Sample: HeLa whole cell lysate (50
µ g/lane)Antibody: Affinity purified Goat anti-SDS 3 (ab3740) used at the concentrations indicated.
Detection: ECL exposed for 2 minutes.
Sample: HeLa whole cell lysate (50
µg/lane) Antibody: Affinity purified Goat anti-SDS 3 (ab3740) used at the concentrations indicated.
Detection: ECL exposed for 2 minutes.
参考文献 (2)
ab3740 は 2 報の論文で使用されています。
- Ramakrishna S et al. Hyaluronan Binding Motifs of USP17 and SDS3 Exhibit Anti-Tumor Activity. PLoS One 7:e37772 (2012). WB ; Human . PubMed: 22662218
- Ramakrishna S et al. K63 specific deubiquitination of SDS3 by USP17 regulates HDAC activity. J Biol Chem : (2011). IP ; Human . PubMed: 21239494
