Anti-SCRN1 抗体 (ab105355)
Key features and details
- Rabbit polyclonal to SCRN1
- Suitable for: ICC/IF, WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
-
製品名
Anti-SCRN1 antibody -
製品の詳細
Rabbit polyclonal to SCRN1 -
由来種
Rabbit -
アプリケーション
適用あり: ICC/IF, WB, IHC-Pmore details -
種交差性
交差種: Human -
免疫原
20 amino acid synthetic peptide to a region within the C-terminus of Human SCRN1 (NP_001138985).
-
ポジティブ・コントロール
- Human kidney tissue
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at 4°C (stable for up to 12 months). Store at -20°C or -80°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
-
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab105355の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
ICC/IF |
Use a concentration of 20 µg/ml.
|
|
WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 46 kDa.
|
|
IHC-P |
Use a concentration of 5 µg/ml.
|
特記事項 |
---|
ICC/IF
Use a concentration of 20 µg/ml. |
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 46 kDa. |
IHC-P
Use a concentration of 5 µg/ml. |
ターゲット情報
-
機能
Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium. -
配列類似性
Belongs to the peptidase C69 family. Secernin subfamily. -
細胞内局在
Cytoplasm. - Information by UniProt
-
参照データベース
- Entrez Gene: 9805 Human
- Omim: 614965 Human
- SwissProt: Q12765 Human
- Unigene: 520740 Human
-
別名
- KIAA0193 antibody
- OTTHUMP00000202313 antibody
- SCRN 1 antibody
see all
画像
-
All lanes : Anti-SCRN1 antibody (ab105355) at 1 µg/ml
Lane 1 : Human kidney tissue lysate in the absence of blocking peptide
Lane 2 : Human kidney tissue lysate in the presence of blocking peptide
Predicted band size: 46 kDa -
ab105355, at 5ug/ml, staining SCRN1 in Human kidney tissue by immunohistochemistry.
-
Immunofluorescence of SCRN1 in Human Kidney cells using ab105355 at 20 ug/ml.
プロトコール
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (1)
ab105355 は 1 報の論文で使用されています。
- Lindhout FW et al. VAP-SCRN1 interaction regulates dynamic endoplasmic reticulum remodeling and presynaptic function. EMBO J 38:e101345 (2019). PubMed: 31441084