製品の概要

  • 製品名

    SCH 23390 hydrochloride, D1-like dopamine receptor antagonist
  • 製品の詳細

    Selective D1-like dopamine receptor antagonist
  • 生理活性の詳細

    Selective D1-like dopamine receptor antagonist. Ki values are 0.2 (D1), 0.3 (D5), 1100 (D2), 800 (D3) and 3000 nM (D4). Some activity at 5-HT receptors (Ki values are 6.3 and 14.8 nM for 5-HT1C and 5-HT2C, respectively). Antipsychotic properties. Centrally active following subcutaneous administration.
  • 精製度

    > 99%
  • CAS 番号

    125941-87-9
  • 構造式

    Chemical Structure

製品の特性

参考文献

This product has been referenced in:

  • Schlenker EH In hamsters the D1 receptor antagonist SCH23390 depresses ventilation during hypoxia. Brain Res 1187:146-53 (2008). Read more (PubMed: 18036574) »
  • Millan MJ  et al. The "selective" dopamine D1 receptor antagonist, SCH23390, is a potent and high efficacy agonist at cloned human serotonin2C receptors. Psychopharmacology (Berl) 156:58-62 (2001). Read more (PubMed: 11465634) »
  • Bourne JA SCH 23390: the first selective dopamine D1-like receptor antagonist. CNS Drug Rev 7:399-414 (2001). Read more (PubMed: 11830757) »
  • Briggs CA  et al. Activation of the 5-HT1C receptor expressed in Xenopus oocytes by the benzazepines SCH 23390 and SKF 38393. Br J Pharmacol 104:1038-44 (1991). Read more (PubMed: 1687364) »
See all 2 Publications for this product

レビューと Q&A

Answer

SCH 23390 hydrochloride (ab120597) n’est pas vendu en solution mais en poudre qui doit être dilué dans de l’eau. Ce produit est soluble dans de l’eau jusqu’a 100 mM.

Vous avez effectivement raison, que la solution finale sera acide.

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