製品の概要

  • 製品名

    SB 206553 hydrochloride, 5-HT2B and 5-HT2C receptor antagonist
  • 製品の詳細

    Potent, selective 5-HT2B and 5-HT2C receptor antagonist
  • 生理活性の詳細

    Potent and selective 5-HT2B and 5-HT2C serotonin receptor antagonist (pKi values are 7.92 (5-HT2C), 5.78 (5-HT2A), 7.65 (5-HT2B), 1A), 1D), 1E) and 1F). Centrally active following oral administration.

  • 精製度

    > 99%
  • CAS 番号

    158942-04-2
  • 構造式

    Chemical Structure

製品の特性

参考文献

This product has been referenced in:

  • Knight AR  et al. Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors. Naunyn Schmiedebergs Arch Pharmacol 370:114-23 (2004). Read more (PubMed: 15322733) »
  • Kennett GA  et al. In vitro and in vivo profile of SB 206553, a potent 5-HT2C/5-HT2B receptor antagonist with anxiolytic-like properties. Br J Pharmacol 117:427-434 (1996). Read more (PubMed: 8821530) »

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