製品の概要

  • 製品名

    (S)-(-)-Raclopride, D2 receptor antagonist
  • 製品の詳細

    D2 receptor antagonist
  • 生理活性の詳細

    High affinity (Kd = 1.2 nM) and high selectivity for D2 receptors in vitro and in vivo (IC50 = 32 nM). Centrally active following systemic administration.
  • 精製度

    > 99%
  • CAS 番号

    84225-95-6
  • 構造式

    Chemical Structure

製品の特性

参考文献

This product has been referenced in:

  • Kopp J  et al. Effect of raclopride on dopamine D2 receptor mRNA expression in rat brain. Neuroscience 47:771-9 (1992). Read more (PubMed: 1533704) »
  • Ogren SO  et al. The selective dopamine D2 receptor antagonist raclopride discriminates between dopamine-mediated motor functions. Psychopharmacology (Berl) 90:287-94 (1986). Read more (PubMed: 2947255) »
  • Köhler C  et al. Specific in vitro and in vivo binding of 3H-raclopride. A potent substituted benzamide drug with high affinity for dopamine D-2 receptors in the rat brain. Biochem Pharmacol 34:2251-9 (1985). Read more (PubMed: 4015674) »

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