製品の概要

  • 製品名

    Ropinirole hydrochloride, D2-like receptor agonist
  • 製品の詳細

    Selective D2-like receptor agonist
  • 別名

    • SKF-101468
  • 生理活性の詳細

    Selective D2-like receptor agonist. Displays high affinity for D2 and D3 but little for D1 receptors (Ki values are 7.2, 22 and >7000 nM, respectively). Shows anti-Parkinsonian activity.
  • 精製度

    > 99%
  • CAS 番号

    91374-20-8
  • 構造式

    Chemical Structure

製品の特性

参考文献

This product has been referenced in:

  • McCall RB  et al. Sumanirole, a highly dopamine D2-selective receptor agonist: in vitro and in vivo pharmacological characterization and efficacy in animal models of Parkinson's disease. J Pharmacol Exp Ther 314:1248-56 (2005). Read more (PubMed: 15980060) »
  • Millan MJ  et al. S32504, a novel naphtoxazine agonist at dopamine D3/D2 receptors: II. Actions in rodent, primate, and cellular models of antiparkinsonian activity in comparison to ropinirole. J Pharmacol Exp Ther 309:921-35 (2004). Read more (PubMed: 14978195) »
  • Eden RJ  et al. Preclinical pharmacology of ropinirole (SK&F 101468-A) a novel dopamine D2 agonist. Pharmacol Biochem Behav 38:147-54 (1991). Read more (PubMed: 1673248) »

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