Anti-RNF138/HSD-4 抗体 (ab92730)
Key features and details
- Rabbit polyclonal to RNF138/HSD-4
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-RNF138/HSD-4 antibody
RNF138/HSD-4 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to RNF138/HSD-4 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ・コントロール
- WB: MCF7 cell lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.87% Sodium chloride, 50% Glycerol (glycerin, glycerine)
Without Mg2+ and Ca2+ -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab92730の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB | (1) |
1/500 - 1/1000. Predicted molecular weight: 28 kDa.
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特記事項 |
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WB
1/500 - 1/1000. Predicted molecular weight: 28 kDa. |
ターゲット情報
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機能
E3 ubiquitin-protein ligase. Together with NLK, involved in the ubiquitination and degradation of TCF/LEF. Also exhibits auto-ubiquitination activity in combination with UBE2K. May act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway. -
パスウェイ
Protein modification; protein ubiquitination. -
配列類似性
Contains 1 RING-type zinc finger. -
ドメイン
The RING-type zinc finger domain mediates binding to an E2 ubiquitin-conjugating enzyme. -
翻訳後修飾
Auto-ubiquitinated.
Phosphorylated upon DNA damage, probably by ATM or ATR. - Information by UniProt
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参照データベース
- Entrez Gene: 51444 Human
- Entrez Gene: 56515 Mouse
- Entrez Gene: 94196 Rat
- SwissProt: Q8WVD3 Human
- SwissProt: Q9CQE0 Mouse
- SwissProt: Q99PD2 Rat
- Unigene: 302408 Human
- Unigene: 253542 Mouse
see all -
別名
- E3 ubiquitin protein ligase RNF138 antibody
- E3 ubiquitin-protein ligase RNF138 antibody
- hNARF antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab92730 は 1 報の論文で使用されています。
- Fu SJ et al. Ubiquitin Ligase RNF138 Promotes Episodic Ataxia Type 2-Associated Aberrant Degradation of Human Cav2.1 (P/Q-Type) Calcium Channels. J Neurosci 37:2485-2503 (2017). PubMed: 28167673